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A sensory receptor that responds to pain.

[Latin nocēre, to hurt; see nocent + (re)ceptor.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
The sensitivity of nociceptive neuron is adjusted by a large variety of mediators in the extracellular space.
CB2 receptor agonists contributed to anti-nociception in other models of both inflammatory and nociceptive pain by suppressing the local secretion of pro-inflammatory factors by non-neural cells, which sensitize neighboring nociceptive neuron terminals.
2B), suggesting that it may represent a novel early response to nociceptive neuron activation.
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures.
According to the company, the Kappa-Opioid Receptors (KORs) are expressed in peripheral nociceptive neurons, immune cells and synovial and cartilage tissue are emerging as a novel and attractive target for the treatment of pain and itch (pruritus).
The phosphoinositide-interacting regulator of-TRP (Pirt) is a transmembrane protein that is expressed in most nociceptive neurons in the dorsal root ganglia (DRG) in the peripheral nerve system (PNS).
VGSCs in primary nociceptive neurons of the TG are involved in pain transduction and transmission processes in orofacial regions [16-18].
Vogt, "Distribution and properties of visceral nociceptive neurons in rabbit cingulate cortex," Pain, vol.
Sensitization of the central nociceptive neurons in the TCC takes place in response to strong dural noxious inputs seen in secondary headache syndromes such as meningitis, subarachnoid hemorrhage, and experimental headaches [9].
This scenario characterized by the exacerbation of superoxide anion production propagates the inflammatory response resulting in sensitization of primary nociceptive neurons [7].
Translocation is necessary to allow phosporylation by PKC[epsilon] of specific cellular targets located in the plasma membrane in nociceptive neurons [16,17], including TRPV1 (Transient Receptor Potential Vanilloid 1) ion channels [18] and several other targets involved in nociceptor sensitization and excitability.