nondisjunction

(redirected from Non-disjunction)
Also found in: Thesaurus, Medical, Encyclopedia.

non·dis·junc·tion

 (nŏn′dĭs-jŭngk′shən)
n.
The failure of paired chromosomes or sister chromatids to separate and go to different cells during meiosis.

non′dis·junc′tion·al adj.

nondisjunction

(ˌnɒndɪsˈdʒʌŋkʃən)
n
(Genetics) the failure of paired homologous chromosomes to move to opposite poles of the cell during meiosis
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nondisjunction - meiosis in which there is a failure of paired homologous chromosomes to separate; results in an abnormal number of chromosomes in the daughter cells
meiosis, miosis, reduction division - (genetics) cell division that produces reproductive cells in sexually reproducing organisms; the nucleus divides into four nuclei each containing half the chromosome number (leading to gametes in animals and spores in plants)
References in periodicals archive ?
The main cause of deterioration of oocyte quality is meiotic non-disjunction (20).
Aneuploidy arising from chromosomal non-disjunction (NDJ) is particularly problematic for students, since it arises in the context of meiosis, itself a challenging subject.
Subsequently non-disjunction and chromosome loss (single or more), in these cells may lead to aneuploidy and mosaicism in cleavage and blastocyst stage embryos.

Full browser ?