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Related to Normoblasts: polychromatophilic erythroblast


An erythroblast, especially one that is developing normally, in contrast with an abnormal megaloblast.

[German Normoblast : norm(al), normal (from Late Latin normālis; see normal) + -blast, -blast (from Greek blastos, bud, germ).]

nor′·mo·blas′tic (-blăs′tĭk) adj.


n. normoblasto, célula roja precursora de los eritrocitos en los humanos.
References in periodicals archive ?
(2) These inclusions appear in neutrophils and morphologically and cytochemically resemble Howell-Jolly bodies of normoblasts in abnormal erythropoiesis.
A bone marrow biopsy report revealed diffuse infiltration of Langerhans cells with vesicular nuclear chromatin, irregular nuclear contours, pale cytoplasm with phagocytosed normoblasts, and mature erythrocytes.
falciparum cases and only 20 (2.8%) cases showed normoblasts indicating erythroid hyperplasia/ stimulation.
Peripheral blood smear showed microcytic, hypochromic red blood corpuscles with immature white blood cells (WBCs; myleocytes, metamyleocytes, and bandforms) and normoblasts (3-4/100 WBC).
Phagocytic vesicles contained red blood cells and normoblasts, neutrophils and platelets.
Bone marrow aspiration showed hypercellularity, with 45% myeloblasts, 15% promyelocytes, 7% myelocytes, 4% metamyelocytes, 1% eosinophils, 2% neutrophils, 15% lymphocytes, and 11% normoblasts. Wright staining of a bone marrow smear showed large (2-4 [micro]m) round-to-oval, hyaline-structured eosinophilic granules (pseudo Chediak-Higashi [PCH] granules) within 15% of the blast cells, promyelocytes, and myelocytes (Figure).
Megakaryocytes and normoblasts are derived from a common committed progenitor cell, the CFU-GEMM (colony-forming unit, granulocytic, erythroid, myelomonocytic).
Routine full blood counts showed that, on average, the SCD patients had a normocytic, normochromic anaemia with a high white cell count, the latter usually indicative of excess normoblasts in the peripheral blood.
These give rise to precursors that are microscopically recognisable as normoblasts comprising the red cells series that include erythroid islands (Fig.