nucleophilicity


Also found in: Medical, Encyclopedia, Wikipedia.

nucleophilicity

(ˌnjuːklɪəʊfɪˈlɪsɪtɪ)
n
(Chemistry) chem the quality of being nucleophilic
References in periodicals archive ?
In MEP analysis, electrophilicity and nucleophilicity is explained on the basis of different color codes, red color indicates nucleophilic and blue color reflects electrophilic site [43].
Dinitropyridyl (DNPy) glycosides--the first glycosyl donor prepared using the nucleophilicity of sugar hemiacetals--.
Nucleophilicity, interatomic distance between electronegative heteroatoms, and electron donor capability of heteroatoms are all important model variables.
Hydroperoxides are very good nucleophiles because of the alpha effect, whereby interaction of lone electron pairs on two adjacent oxygen atoms increases nucleophilicity [78], and this explains the reactivity of hydrogen peroxide with aldehydes.
Moreover, 4-VP can be chemically modified to prepare a charged particle with tunable alkyl chain length and structure by the reaction with various quartemization agents because of the nucleophilicity of the nitrogen atoms on the pyridine ring [35, 36].
This high electron density leads to strong boron-based nucleophilicity and extremely high reduction potentials both highly novel phenomena.
It is assumed that high nucleophilicity and high electrophilicity are in opposite ends of this scale and, therefore, a molecule that shows a low electrophilicity power can be considered as a nucleophile (Parr et al.
Oximes reactivate phosphylated cholinesterase by displacing the phosphoryl moiety from the enzyme by virtue of their high affinity for the enzyme and their powerful nucleophilicity.
The reason fluoride is so destructive to biomolecules is that it has a greater nucleophilicity than hydroxyl groups, and can substitute for OH on carbon )n all the important biomolecules.
Thus, only when triethylamine (TEA) was added to raise the nucleophilicity of 3c, the desired product 4c was formed with an excellent yield of 97% (Table 1, entry 3).