nude mouse

(redirected from Nude mice)
Also found in: Thesaurus, Medical.
Related to Nude mice: SCID mice

nude′ mouse′

a hairless mutant laboratory-bred mouse having an immune system deficiency and able to accept grafts of foreign tissue.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nude mouse - a mouse with a genetic defect that prevents them from growing hair and also prevents them from immunologically rejecting human cells and tissues; widely used in preclinical trials
mouse - any of numerous small rodents typically resembling diminutive rats having pointed snouts and small ears on elongated bodies with slender usually hairless tails
Mentioned in ?
References in periodicals archive ?
To investigate in vivo survival, we respectively injected Vivo nanofat and nanofat subcutaneously to the back of 8-week-old male BALB/c nude mice.
We imported 60 nude mice from France because they do not have an immune system.
Nude mice bearing Bel-7402 were administered intraperitoneally at different doses of dioscin and 5-FU (5-Fluorouracil) treatment was used as a control.
The biocompatibility, release kinetics, and potential of MSC-CM loaded biomaterials for bone regeneration will be tested in vitro on cells involved in bone formation (MSC, monocytes, osteoclasts, macrophages, and endothelial cells) and in vivo by implanting the biomaterials in subcutis sites and segmented femoral defects in nude mice.
Previous winners have included Goblin proofing One's Chicken Coop, Proceedings of the Second International Workshop on Nude Mice, Bombproof Your Horse, Greek Rural Postmen and their Cancellation Numbers, The Joy of Chickens and The Book of Marmalade.
Twelve male BALB/c nude mice (4 weeks of age) were obtained from the Shanghai Laboratory Animal Research Center (Shanghai, China) and housed in the mouse barrier facility of the Institute for Nutritional Sciences, SIBS CAS.
Our findings warrant further investigation with a larger cohort of nude mice or possibly human subjects.
This overall attack rate is consistent with previous outbreaks of LCMV in hamsters and nude mice at research facilities (10,12,13).
IMPLICATIONS: Further investigations are warranted to determine the following: 1) the role of galectin-3 in normal and cancerous prostate tissues and 2) the ability of modified citrus pectin to inhibit human prostate metastasis in nude mice.
Previous studies have showed that laminar flow cabinet in common laboratory animal facility can provide a local SPF condition and can be successfully used to breed nude mice (Li et al.
To establish a brain metastasis melanoma variant, the investigators first injected WM239 melanoma cells into the subcutaneous space of nude mice and then allowed the tumors to develop before surgically removing them.