complement fixation

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complement fixation

n.
The binding of active serum complement to an antigen-antibody pair. It is the basis for various diagnostic tests to detect the presence of a specific antigen or antibody.

com′plement fixa`tion



n.
the binding of complement to immune complexes or to certain foreign surfaces, as those of invading microorganisms.
[1905–10]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.complement fixation - an immune response in which an antigen-antibody combination inactivates a complement (so it is unavailable to participate in a second antigen-antibody combination)
immune reaction, immune response, immunologic response - a bodily defense reaction that recognizes an invading substance (an antigen: such as a virus or fungus or bacteria or transplanted organ) and produces antibodies specific against that antigen
References in periodicals archive ?
The organism was first isolated in 1906 by Jules Jean Baptiste Vincent Bordet and Octave Gengou.