Oleandrin


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O`le`an´drin


n.1.(Chem.) One of several cardiac glycosides (C32H48O9) found in oleander (Nerium oleander).
Webster's Revised Unabridged Dictionary, published 1913 by G. & C. Merriam Co.
References in periodicals archive ?
When Nerium International launched in 2011, the company name was associated with an ingredient (nerium oleandrin extract) in its first product.
The seeds contain oleandrin and related compounds: odorosides, adigoside, and glucostrospeside [8, 55].
Two toxic cardiac glycosides (cardenolides), oleandrin and neriine, have been isolated from all parts of the plant and reported as positive inotropic, negative chronotropic, cross reactive, and very similar to the toxin in foxglove (Digitalis) [3, 4].
Oleander (Nerium oleander) may also be a constituent and contains antitumour cardiac glycosides [76] such as oleandrin [77].
Oleandrin produces changes in intracellular calcium levels in isolated cardiomyocytes, a real-time fluorescence imaging study comparing adult to neonatal cardiomyocytes.
The letter said: "The department noticed the spread of vegetation such as the highly toxic oleander plant which contains the very toxic materials oleandrin and oleandrigenin, that affects the heart, and causes diarrhea, nausea, abdominal pain, cardiovascular disorder and inflammation of the eyes by direct exposure to the plant." The letter stressed on the need to ban the planting of oleanders in public places and parks, and locations in the reach of children.
Previous studies have revealed the presence of carbohydrates, proteins, phenols, oleandrin and its aglycone oleandrigenin, triterpenoids, a resin, tannins, glucose, a paraffin, ursolic acid, vitamin C and an essential oil in different parts of this plant (Zibbu and Batra, 2010; Zibbu and Batra, 2012).
Faculty and staff in this section routinely test for toxins such as oleandrin and various rodenticides as well as natural substances such as nitrate, copper and lead.
There is reason to believe that at least one ingredient in oleander, namely oleandrin (also dubbed PBI-05204), might have anticancer activity.
Nature lover Reza Khan said nerium oleander which grows in the wet wadi beds of the Hajar mountains is very poisonous and contains toxins like oleandrin and neriine which are cardiac glycosides.
Oleandrin produces changes in intracellular calcium levels in isolated cardiomyocytes: a real-time fluorescence imaging study comparing adult to neonatal cardiomyocytes.