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 (ŏl′ĭ-gō-no͞o′klē-ə-tīd, -nyo͞o′-, ō′lĭ-)
A short polymer of two to twenty nucleotides.


(Biochemistry) a polymer consisting of a small number of nucleotides


(ˌɒl ɪ goʊˈnu kli əˌtaɪd, -ˈnyu-)

a chain of a few nucleotides.
References in periodicals archive ?
The company offers services for DNA, RNA and other oligonucleotides based therapeutics from milligram scale at pre-clinical stage to 1000kg + post commercial launch.
Major factors contributing to the growth of the global oligonucleotide synthesis market include increasing R&D expenses in the pharmaceutical and biotechnology companies, rising demand for synthesized oligonucleotides due to the growing field of molecular diagnostics, increasing government investments to develop genomic technologies, rising venture capital investments, and increasing demand for synthetic genes.
This contract is for the supply, delivery and installation of an oligonucleotide synthesizer, designed to be integrated into the synthesis and purification of oligonucleotides platform of bioimaging Institute of the University of Bordeaux.
This alliance with Girindus allows us to move the development and supply of CRN-based oligonucleotides to a team with exceptional experience and capability thus allowing us to focus on bringing novel therapeutics to patients in need.
Handbook of analysis of oligonucleotides and related products.
The Clarity OTX protocol uses a propriety mixture of chaotropes, detergents, and other dispersants to disrupt intermolecular interactions that are common for oligonucleotides in biological matrices.
Editors Moretti and Rizzo (no affiliations listed) have collected research in the field on the use of oligonucleotides for detecting complementary DNA and RNA such as in DNA microarrays and the synthesis of artificial genes.
Methods: Nuclear extracts from hematopoietic and non-hematopoietic cells are incubated with labeled double stranded oligonucleotides from 50-200 bp in length in EMSA binding buffer.
We have developed a specific chemical process that generates a fluorescent product on annealing of 2 oligonucleotides to each other.
The 2 oligonucleotides harbor adaptors (in lower case) corresponding to universal forward and reverse oligonucleotides that can be used for sequencing after amplification.
Building on our 17 year history in oligonucleotide manufacture and analysis, Dalton can now use its expertise in synthesis and manufacturing of antisense oligonucleotides and their analogs to produce cGMP grade oligonucleotides as required for human clinical testing.
TriLink offers small-scale oligonucleotides for the discovery and pre-clinical stages of drug development to customers exploring a wide variety of DNA or RNA based therapies.