Depression combined with chronic opioid analgesic
use involves more symptoms and comorbidities than depression without chronic opioid use, according to a study of Department of Veterans Affairs patients seen.
Long-term prescription opioid analgesic
use (OAU) for chronic non-cancer pain is defined as daily or near-daily use for 90 days.
San Francisco, California-based research-based development stage biopharmaceutical company Nektar Therapeutics (NASDAQ: NKTR) has provided positive topline results from an oral human abuse potential (HAP) study of NKTR-181, a first-in-class opioid analgesic
, the company said.
Public health detailing-A successful strategy to promote judicious opioid analgesic
Additionally, the number of patients who were prescribed both an opioid analgesic
and benzodiazepine increased by 41 percent between 2002 and 2014, which translates to an increase of more than 2.
misuse and abuse have increased significantly in the United States over the past two decades, and represent major public health concerns due to the risk of coma and fatal respiratory depression associated with opioid analgesic
7% of privately insured women had at least one opioid analgesic
In contrast, two recent case-control studies have demonstrated significantly increased risks for early pregnancy opioid analgesic
use and specific defects.
Two Food and Drug Administration advisory committees have unanimously agreed that the current risk evaluation and mitigation strategy (REMS) for extended-release and long-acting opioid analgesic
medications requires modification in order to better serve its purpose of addressing the ongoing epidemic of opioid abuse and addiction.
Activation of neurons that descend to the spinal cord takes place when using an opioid analgesic
Whilst the prescription rates of opioid analgesic
have seen a historically unprecedented increase over the last two decades, particularly in the US, this has resulted in a dramatic concomitant increase in opioid abuse and dependency.
These medications may be more accessible to children in the home because the number of opioid analgesic
prescriptions has increased, according to data from the U.