(redirected from Opioid receptors)
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Related to Opioid receptors: Opioid Analgesics


Any of various compounds that bind to specific receptors in the central nervous system and have analgesic and narcotic effects, including naturally occurring substances such as morphine; synthetic and semisynthetic drugs such as methadone and oxycodone; and certain peptides produced by the body, such as endorphins. Also called opiate.

o′pi·oid′ adj.


a. any of a group of substances that resemble morphine in their physiological or pharmacological effects, esp in their pain-relieving properties
b. (modifier) of or relating to such substances: opioid receptor; opioid analgesic.


(ˈoʊ piˌɔɪd)

1. any opiumlike substance, as the endorphins produced by the body or the synthetic compound methadone.
2. pertaining to such a substance.


adj & n opioide m
References in periodicals archive ?
Vivitrol is an antagonist, which blocks the activation of opioid receptors and thus the feeling of euphoria.
Selective opioid receptor agonists: These agents target kappa- and/or mu-opioid receptors on peripheral pain-sensing neurons in order to inhibit itch without activating other opioid receptors linked to classic opioid side effects such as respiratory depression, constipation, and addiction.
It works by temporarily binding to opioid receptors in the brain and body and counteracting the effects of opioids.
When opioid drugs are taken, they use opioid receptors that are normally accessed by endorphins to tap into the body's systems.
But now, neuroscientists found a way to activate opioid receptors with light.
Opioid receptors are predominantly expressed in the brain cortex, limbic system, and brain stem.
Because it is an acyclic analog of morphine or heroin, methadone acts on the same opioid receptors as these drugs, and thus has many of the same effects.
For example, capsaicin-induced thermal allodynia is attenuated by stimulating MOR opioid receptors in the central nervous system of rhesus monkeys.
The evidence suggests that there is considerable population of opioid receptors in the septal area.
13 ( ANI ): Scientists have found how the sodium influences the signaling of a major class of brain cell receptors, known as opioid receptors, which could help pave way for new therapeutic approaches to a host of brain-related medical conditions.
It is further classified by its actions as an opioid agonist, creating its effects by stimulating the opioid receptors with both affinity (measure of strength of the interaction between ligand binding to the receptor) and efficacy (measure of strength of effect from the binding to the receptor).
Kappa opioid receptors are especially interesting because of their .