ornithine

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Related to Ornithine transcarbamylase: urea cycle, arginase

or·ni·thine

 (ôr′nə-thēn′)
n.
An amino acid, C5H12N2O2, not found in proteins, formed by hydrolyzing arginine and important in the formation of urea.

[ornith(uric acid), an acid found in birds' urine (ornith(o)- + uric acid) + -ine.]

ornithine

(ˈɔːnɪˌθiːn)
n
(Biochemistry) an amino acid produced from arginine by hydrolysis: involved in the formation of urea in the liver; diaminopentanoic acid. Formula: NH2(CH2)3CHNH2COOH
[C19: from ornithuric (acid) secreted in the urine of birds, from ornitho- + uric]

or•ni•thine

(ˈɔr nəˌθin)

n.
an amino acid, H2N(CH2)3CH(NH2)COOH, obtained by the hydrolysis of arginine and occurring as an intermediate compound in the urea cycle of mammals.
[1880–85; ornith(uric acid), secreted by birds + -ine2]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.ornithine - an amino acid that does not occur in proteins but is important in the formation of urea
amino acid, aminoalkanoic acid - organic compounds containing an amino group and a carboxylic acid group; "proteins are composed of various proportions of about 20 common amino acids"
Translations
Ornithin
ornithine
ornityna

or·ni·thine

n. ornitina, aminoácido que aunque no está presente en las proteínas desempeña un papel importante en el ciclo de la urea.
References in periodicals archive ?
Relative frequency of mutations causing ornithine transcarbamylase deficiency in 78 families.
Mutations and polymorphisms in the human ornithine transcarbamylase (OTC) gene.
The metabolic diseases are divided into those associated with structural damage to the liver (Wilson's, alpha-1 antitrypsin) and those in which the liver is structurally normal and LT is required to replace a life-threatening enzyme deficiency (Crigler-Najjar syndrome, ornithine transcarbamylase deficiency, or hyperoxaluria type 1).
1] The carcinogenic substances currently being investigated include nitrosamine, reactive oxygen species, epidermal growth factor, transforming growth factor, cyclo-oxygenase, mucin and ornithine transcarbamylase.
Urea Cycle Disorders (UCD) are an important group of inborn errors of metabolism resulting from deficiencies of six different enzymes inherited as autosomal recessive, with the exception of Ornithine Transcarbamylase (OTC), which has X-linked inheritance.
Clinical and laboratory observations of thirty-two Japanese male patients with ornithine transcarbamylase deficiency.
Developing adenoviral-mediated in vivo gene therapy for ornithine transcarbamylase deficiency".
Jesse, who was eighteen years old, was participating in a phase I safety study of a gene transfer therapy for ornithine transcarbamylase deficiency (OTCD), a rare metabolic condition.
He was suffering from a potentially fatal disease known as ornithine transcarbamylase deficiency (OTD), which prevents the liver from breaking down protein.
The fact that carriers for various metabolic diseases such as early vascular disease in homocystinuria, hyperammonemic episodes in ornithine transcarbamylase deficiency, presenile cataracts in galactosemia, and so forth (Endres 1997), as well as for AAT deficiency (Feld 1989; Gourley et al.

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