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Related to Orthologue: orthologous genes, paralogous genes


or or·tho·logue  (ôr′thə-lôg′, -lŏg′)
A homologous gene that is related to those in different organisms by descent from the DNA of a common ancestor and that may or may not have the same function.

[Back-formation from orthologous : ortho- + (homo)logous.]

or·thol′o·gous (-thŏl′ə-gəs) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
Identification of the first toll-like receptor gene in passerine birds: TLR4 orthologue in zebra finch (Taeniopygia guttata).
Physiological and cellular responses caused by RNAi-mediated suppression of Snf7 orthologue in western corn rootworm (Diabrotica virgifera virgifera) larvae.
In yeast, the disruption of Sec18p, the yeast orthologue of mammalian Nethylmaleimide sensitive fusion protein, an essential protein for vesicular trafficking between ER, Golgi, and PM, does not inhibit the ER to PM transport [74]; two plasma membrane ABCG transporters, Aus1p and Pdr11p, stimulate cholesterol transport from PM to ER [99].
Atanasova et al., "The VELVET A orthologue VEL1 of Trichoderma reesei regulates fungal development and is essential for cellulase gene expression," PLoS One, vol.
reported the identification and functional characterisation of the avian orthologue of TNFa [109].
Park et al., "In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni," Nature Communications, vol.
Of note, there are some questions about the murine orthologue of Lnc-DC, because this gene was previously identified as Wdnm1-like, and its transcript can be translated into the Wdnm1-like protein in most mammals but with humans as an exception which is possibly unique [38, 39].
= 0.1, coverage = 0.5, percent_identity = 50, adaptive_similarity=0.95, inc_pairs=1, inc_singles= 1, selfblast=1, and unambiguous = 0) [35] was used to generate clusters of orthologue groups, inparalogues were removed, and MUSCLE [36] used to align the remaining sequences and poorly aligned positions were automatically filtered from the alignments using Gblocks [37].
Fluoroquinolone and multidrug resistance phenotypes associated with the overexpression of AcrAB and an orthologue of MarA in Yersinia enterocolitica.