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Having a toxic effect on the structures of the ear, especially on its nerve supply.

o′to·tox·ic′i·ty (-tŏk-sĭs′ĭ-tē) n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Medicine) damage to the ear
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
In brief, the drug dose-dependent hair cell death can be examined with a particular ototoxin, such as neomycin, and subsequent time-lapsed cell regeneration can be investigated with borderline-hair cell death that is achieved by appropriate drug dose [17, 19].
(18) Hypoxemia has been identified as a possible ototoxin according to Duara S et al (19), Leech et al concluded that brainstem auditory nuclei are particularly susceptible to acute hypoxic insults in the neonates.
The chance of acquiring a hearing problem increases by five percent for this risk group owing to low oxygen, ototoxins they received and the noise exposure inside the Intensive Care Unit," he said.
Brozoski, "Cochlear structure and function after round window application of ototoxins," Hearing Research, vol.