Oxamate


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Ox`am´ate


n.1.(Chem.) A salt of oxamic acid.
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The pikas of experimental group were injected with 1 mL of 1 mol/L N-isopropyl oxamate, a specific LDH-C4 inhibitor, in biceps femoris muscle of hind legs, each leg with 500 uL.
176, respectively; 2) 30 min after administration of 1 mL of 1 mol/L N-isopropyl oxamate injected in biceps femoris muscle, the concentration of N-isopropyl oxamate in blood was 0.
Wai-Nang Lee, of the Los Angeles Biomedical Research Institute, and colleagues also discovered an enzyme inhibitor called oxamate, which is known to reduce LDHA activity, functioned in a similar manner and also disrupted the metabolic system of pancreatic cancer cells.
The researchers also found an enzyme inhibitor, oxamate - known to reduce LDHA activity - operated in the same manner: It also disrupted the metabolic system of pancreatic cancer cells.
The researchers found the EGCG disrupted this balance in the same manner that oxamate, a known LDHA inhibitor did.
The researchers also found an enzyme inhibitor oxamate, which is known to reduce LDHA activity, operated in the same manner.
Researchers also found that an enzyme inhibitor, oxamate, which is known to reduce LDHA activity, also disrupted the pancreatic cancer cells metabolic system.
In the second experiment, strip steaks were cut in half and one side was injected with oxamate, an LDH inhibitor.
However, 2-n-decylquinazolin-4-yl-amine (DQA), a potent inhibitor of complex I, and oxamate, an inhibitor of LD, did not significantly influence PDHC activity (Fig.
C(alpha), N-Dilithiophenylhydrazones were prepared in excess lithium diisopropylamide, {LDA), and condensed with ethyl oxanilates or ethyl oxamate to give C-acylated intermediates that could be isolated or cyclized directly with aqueous hydrochloric acid/ tetrahydrofuran (THF) to the targeted 1H-pyrazole-5-carbox-amides.
Similar reactions of polylithiated hydrazones with either dilithiated ethyl oxamate, or lithiated ethyl oxanilates followed by acid cyclization with acid resulted in select 1H-pyrazole-5-carboxamides.