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 (glī′kō-prō′tēn′, -tē-ĭn)
Any of a group of conjugated proteins having a carbohydrate as the nonprotein component.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌɡlaɪkəʊˈprəʊtiːn) ,




(Biochemistry) any of a group of conjugated proteins containing small amounts of carbohydrates as prosthetic groups. See also mucoprotein
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌglaɪ koʊˈproʊ tin, -ti ɪn)

any of a group of complex proteins, as mucin, containing a carbohydrate combined with a simple protein.
Also called gly`co•pep′tide (-ˈpɛp taɪd)
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.glycoprotein - a conjugated protein having a carbohydrate component
mucin - a nitrogenous substance found in mucous secretions; a lubricant that protects body surfaces
compound protein, conjugated protein - a protein complex combining amino acids with other substances
erythropoietin - a glycoprotein secreted by the kidneys that stimulates the production of red blood cells
CD4, cluster of differentiation 4 - a glycoprotein that is found primarily on the surface of helper T cells; "CD4 is a receptor for HIV in humans"
CD8, cluster of differentiation 8 - a membrane glycoprotein that is found primarily on the surface of cytotoxic T cells
lectin - any of several plant glycoproteins that act like specific antibodies but are not antibodies in that they are not evoked by an antigenic stimulus
mucoid - any of several glycoproteins similar to mucin
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
P-glycoprotein (P-gp) is as a carrier protein encoded on the seventh chromosome (7q21) by the MDR 1 gene.
Oraxol is an innovative oral formulation of paclitaxel, an effective and commonly used anti-cancer chemotherapy, combined with HM30181A, a novel gastrointestinal tract specific P-glycoprotein pump inhibitor.
The authors reported that significant pharmacokinetic interactions were more likely with drugs that were substrates for CYP3A4 and/or p-glycoprotein (ABCB1) and were less likely in studies that investigated SJW products with low-hyperforin content.
Inhibitors of P-glycoprotein (P-gp) affect drug-drug interactions, altering pharmacokinetic properties, metabolism, and the eventual excretion of active drugs; concentration (by retention in the body) is thus indirectly enhanced (19, 29).
In rats, Fabien Caille and colleagues describe the labelling of metoclopramide and show that its transporter-mediated plasma clearance into hepatocytes is saturable and not modified by the P-glycoprotein inhibitor tariquidar.
We suggest that rivaroxaban package insert should include more information on medications considered to be inhibitors of CYP3A4 and P-glycoprotein system.
The mechanisms underlying MDR are complex; however, ATP binding cassette (ABC) transmembrane proteins, particularly the multidrug resistance 1 gene (MDR1), which encodes transmembrane protein P-glycoprotein (P-gp), play an important role [5].
(27,28) These interactions occur due to AED induction of the CYP3A4 enzyme and effects on the P-glycoprotein (P-gp) efflux pump.
Multidrug resistance (MDR) involves a variety of mechanisms, including increases in P-glycoprotein (P-gp), multi-drug resistance-associated protein (MRP), breast cancer resistance protein (BCRP) and lung resistance protein (LRP), decreases in Topo-II activity, elevation of glutathione S-transferase (GST), and alterations of protein kinase C (PKC) function (6).
Box The function of P-glycoprotein P-glycoprotein is known as a multi-drug resistance protein because it is involved in resistance mechanisms for a number of drugs.
observed that the anti-skin cancer effects of ursolic acid are augmented by P-glycoprotein inhibitors and that ursolic acid and the stilbene resveratrol, a potent antioxidant, work synergistically, although not by blocking P-glycoprotein.
Furthermore, tacrolimus is also a substrate of P-glycoprotein (1).