inhibitor

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Related to PDE inhibitor: phosphodiesterase type 5 inhibitors, PDE5

in·hib·i·tor

also in·hib·it·er  (ĭn-hĭb′ĭ-tər)
n.
One that inhibits, as a substance that retards or stops a chemical reaction.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

inhibitor

(ɪnˈhɪbɪtə)
n
1. Also called: inhibiter a person or thing that inhibits
2. (Chemistry) Also called: anticatalyst a substance that retards or stops a chemical reaction. Compare catalyst
3. (Biochemistry) biochem
a. a substance that inhibits the action of an enzyme
b. a substance that inhibits a metabolic or physiological process: a plant growth inhibitor.
4. (General Physics) any impurity in a solid that prevents luminescence
5. (Astronautics) an inert substance added to some rocket fuels to inhibit ignition on certain surfaces
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

in•hib•i•tor

or in•hib•it•er

(ɪnˈhɪb ɪ tər)

n.
1. one that inhibits.
2. a substance that slows or stops a chemical reaction.
[1865–70]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.inhibitor - a substance that retards or stops an activity
substance - a particular kind or species of matter with uniform properties; "shigella is one of the most toxic substances known to man"
angiotensin II inhibitor - an agent that retards or restrains the action of angiotensin II
antioxidant - substance that inhibits oxidation or inhibits reactions promoted by oxygen or peroxides
anticatalyst - (chemistry) a substance that retards a chemical reaction or diminishes the activity of a catalyst
moderator - any substance used to slow down neutrons in nuclear reactors
activator - (biology) any agency bringing about activation; a molecule that increases the activity of an enzyme or a protein that increases the production of a gene product in DNA transcription
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

in·hib·i·tor

n. inhibidor, agente que causa una inhibición;
fusion ______ de fusión.
English-Spanish Medical Dictionary © Farlex 2012

inhibitor

n inhibidor m; angiotensin converting enzyme — inhibidor de la enzima convertidora de angiotensina; cholinesterase — inhibidor de la colinesterasa; fusion — inhibidor de (la) fusión; integrase — inhibidor de la integrasa; monoamine oxidase — inhibidor de la monoaminooxidasa; non-nucleoside reverse transciptase — (NNRTI) inhibidor no nucleósido de la transcriptasa inversa or reversa; nucleoside reverse transcriptase — (NRTI) inhibidor nucleósido de la transcriptasa inversa or reversa; nucleotide reverse transcriptase — (NtRTI) inhibidor nucleótido de la transcriptasa inversa or reversa; protease — inhibidor de la proteasa; proton pump — inhibidor de la bomba de protones; selective serotonin reuptake — inhibidor selectivo de la recaptación de serotonina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Surprisingly, both the TRP channel modulator 2-APB and the PDE inhibitor theophylline were found to inhibit movement of the sea urchins (Fig.
It has been demonstrated that cAMP can be hydrolyzed by phosphodiesterase (PDE); therefore, we evaluated whether elevation of cAMP by PDE inhibitor contributes to TPPU and 14,15-EET promotion of FSK-mediated synaptic potentiation.
Differently, ilexsaponin [A.sub.1] (9) with low binding efficiency turned out to be the strongest PDE inhibitor (332.0 [micro]M and 22.4 [micro]M against PDEI and PDE5A, resp.) among the components tested in vitro.
where, [[cAMP].sub.C1] and [[cAMP].sub.C2] are the cAMP concentrations in compartments 1 and 2, A[C.sub.basal] is basal adenylyl cyclase activity (cAMP synthesis), [V.sub.maX] is the maximal rate of cAMP hydrolysis by PDE, [K.sub.m1] is the Michaelis constant for PDE activity, [I] is the concentration of PDE inhibitor, KI is the inhibitor dissociation constant, [k.sub.1] and [k.sub.2] are the cAMP flux coefficients between C1 and C2, and [V.sub.1] and [V.sub.2] are the volumes of C1 and C2.
In the presence of low levels of PDE4, [beta]-agonist (but not PDE inhibitor) can inhibit collagen gel contraction.
The reasons panelists gave for voting against approval included what some described as the "meager" or modest beneficial effect of roflumilast in studies, the need to compare it with other COPD treatments like theophylline (a nonspecific PDE inhibitor and the only PDE inhibitor marketed in the United States), and the need to evaluate its efficacy when added to standard COPD treatments like inhaled corticosteroids.
The non-specific PDE inhibitor ibudilast induced a favourable immune shift in certain T-cell subtypes and natural killer (NK) cells in human MS.
Moreover, as described in our PDE experiments, caffeine also act with weak affinity as PDE inhibitor and can also stimulate lipolysis in this way.
Optionally, the method includes administration of a type IV PDE inhibitor. (US 7,427,606)