CJD

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CJD

abbr.
Creutzfeldt-Jakob disease
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

CJD

abbreviation for
(Pathology) Creutzfeldt-Jakob disease
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.CJD - rare (usually fatal) brain disease (usually in middle age) caused by an unidentified slow virus; characterized by progressive dementia and gradual loss of muscle control
brain disease, brain disorder, encephalopathy - any disorder or disease of the brain
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

CJD

[ˌsiːˌdʒeɪˈdiː] n (=Creutzfeld Jacob disease) → MCJ f
Collins English/French Electronic Resource. © HarperCollins Publishers 2005

CJD

abbr of Creutzfeldt-Jakob diseaseCJK f
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007
References in periodicals archive ?
Our data confirm that elk CWD prions can convert the human Pr[P.sup.C], at least in vitro, and show that the homologous PRNP polymorphisms at codon 129 and 132 in humans and cervids affect conversion efficiency.
Remarkably, disease transmission of brain extracts from Tg animals overexpressing the P101L mutation neither occurred to wild-type nor to Tg mice expressing MoPrP-P101L from two transgene copies that do not develop disease spontaneously in their natural lifespan [27], which is in full agreement with a previous study from Manson's group showing that PRNP gene-targeted 101LL mice expressing MoPrPP101L failed to develop the neurodegenerative disease spontaneously [28].
Estibeiro et al., "Genetic basis of Creutzfeldt-Jakob disease in the United Kingdom: a systematic analysis of predisposing mutations and allelic variation in the PRNP gene," Human Genetics, vol.
Son heredadas de manera autosomica dominante y cosegregan con mutaciones en el gen PRNP (11).
For comparison and validation purposes, we also analyzed PRNP genotypes by use of Big-Dye Terminator sequencing on a Model AB13100 sequencer (Applied Biosystems), as described elsewhere.
Mice have been raised in whom Prnp (the designation for the prion protein gene in mice) has been eliminated or knocked out of their genome.
Sequencing revealed the same PRNP sequence in animals 4 and 8 (GenBank accession nos.
An allelic polymorphism of codon 129 of human PRNP modulates disease susceptibility and clinicopathologic phenotype in CJD (11).
Polymorphism at codon 129 of the human PrP gene (PRNP), where methionine (Met) or valine (Val) can be encoded, strongly affects susceptibility to human prion diseases (16-20).
A promoter with the 23-bp insertion of the PRNP gene binding strongly to RP58 (repressor protein 58) affected production traits in cattle (Sander et al., 2005 ).