To remove some of these restrictions, investigators developed
paromomycin. (7) On the other hand, studies examined the impact of the
paromomycin has different characteristics and results.
Eight of those patients were not treated properly (they received
paromomycin ointment, itraconazole, and/or intralesional sodium stibogluconate, or no treatment); 3 received IV SSG, and only 1 received IV L-AmB 3 mg/kg for 5 consecutive days and a 6th dose on day 10.
These medical treatments contain oral metronidazole therapy for 5-10 days and to eradicate colonization its followed by a luminal agent as
paromomycin, iodoquinol or diloxanide furoate for 5-20 days.
Nowadays, different combination therapy strategies including miltefosine,
paromomycin and amphotericin B are being tested in multiple controlled clinical trials in various geographical areas of endemicity, both in South Asia and East Africa.4 The Regional Technical Advisory Group (RTAG) for Kala-azar elimination has recommended miltefosine monotherapy as first-line therapy for treatment of visceral leishmaniasis in endemic countries like India, Nepal and Bangladesh.4 In conclusion, miltefosine a well-tolerated oral drug, might play a fundamental role in the management of leishmaniasis patients.
Nitroimidazole-resistant vaginal trichomoniasis treated with
paromomycin. Eur J Obstet Gynecol Reprod Biol 2001; 96: 11920.
(2, 7) Also, the clinical management of VL is undergoing rapid changes with the use of liposomal forms of Amphotericin B and also due to the use of various combinations of miltefosine, amphotericin B,
paromomycin etc.
To get rid of the parasites infesting the intestines, doctors normally prescribe anti-parasitic treatments like
Paromomycin or Metronizal to destroy any traces of amoeba in intestinal tissue and other surrounding organs.
Following therapy for invasive amebiasis, treatment with a luminal agent (
paromomycin, iodoquinol, or nitazoxanide) to eliminate intraluminal cysts is warranted, even if stool microscopy is negative [3].
Dec 17, 2012: PATHs Drug Development Program Announces Successful Completion Of Phase IIIb Clinical Trial Of
Paromomycin Intramuscular Injection In Bangladesh 96
The parameters for positive results of the tetracycline antibiotics tested are: oxytetracycline (10 [micro]g/kg), tetracycline (10 [micro]g/kg), chlortetracycline (10 [micro]g/kg), and doxycycline (20 [micro]g/kg); the parameters for positive results of the aminoglycoside antibiotics tested are: dihydrostreptomycin (10 [micro]g/ kg), gentamicin (50 [micro]g/kg), hygromycin (20 [micro]g/kg), kanamycin (20 [micro]g/kg), neomycin (20 [micro]g/kg),
paromomycin (25 [micro]g/kg), spectinomycin (50 [micro]g/kg), and streptomycin (20 pg/ kg).
Anti-Cryptosporidium activity of albendazole, metronidazole and
paromomycin in experimentally infected cattle.