pentamidine


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Related to pentamidine: Pentamidine isethionate

pentamidine

(pɛnˈtæmɪˌdiːn; -dɪn)
n
(Pharmacology) a drug used to treat protozoal infections, esp pneumonia caused by Pneumocystis carinii in patients with AIDS

pen•tam•i•dine

(pɛnˈtæm ɪˌdin, -dɪn)

n.
an antiprotozoal substance, C19H24N4O2, used in treating pneumocystis pneumonia, leishmaniasis, and trypanosomiasis.
[1941; pent(ane) + amidine any of a group of compounds with the CN2H3 group (amide + -ine2)]
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Table 6 Medications that Cause Hyperkalemia * ACE inhibitors * Angiotensin receptor blockers * Antifungals * Beta-blockers * Calcium channel blockers * Antibiotics (penicillin G) * Cyclosporine * Digoxin * Aldosterone antagonist * Heparin * Hypertonic solutions (mannitol, glucose) * Non-steroidal anti-inflammatory drugs (NSAIDs) * Pentamidine * Tacrolimus * Potassium sparing diuretics Sources: Crawford, 2014; Eliacik et al.
Other treatments include cryotherapy, heat therapy, pentamidine, azoles, amphotericin B, allopurinol, and paromomycin.
11] In a previous study, pancreatitis was associated with gallstones, intravenous drug abuse, pentamidine intake, and Pneumocystis jiroveci and Mycobacterium avium-intracellulare infections.
04 uM) exhibited moderate to weak anti-leishmanial potential, if compared with the standard pentamidine (IC50 = 5.
Both Raphanus caudatus extract as well as Pentamidine showed significant (pless than 0.
Trials showed that aerosolized pentamidine could keep people with aids from getting PCP, but the FDA was reluctant to release it because the trial had no placebo arm.
6) However aerosolized pentamidine may be an independent risk factor.
Two of these 6 chemicals--raloxifene hydrochloride and pentamidine isethionate--were also predicted to have low potential for BBB penetration.
Drug therapies, including pentavalent antimonials, pentamidine (Nebupent[TM]), amphotericin B (Fungizone[TM]), and miltefosine (Miltex[TM]), are currently employed to treat leishmaniasis, each with different mechanisms of action [8].
A randomized clinical trial comparing meglumine antimoniate, pentamidine and amphotericin B for the treatment of cutaneous leishmaniasis by Leishmania guyanensis.
Second-line drugs include pentamidine and amphotericin B; however have also showed highly toxic effects.
Nephrotoxicity and hyperkalemia in patients with acquired immunodeficiency syndrome treated with pentamidine.