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Related to Peptidoglycans: murein, Proteoglycans


 (pĕp′tĭ-dō-glī′kən, -kăn′)
A polymer found in the cell walls of prokaryotes that consists of polysaccharide and peptide chains in a strong molecular network. Also called mucopeptide, murein.

[peptide + glycan, a polysaccharide.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌpɛptɪdəʊˈɡlaɪkæn; ˌpɛptaɪdəʊ-)
(Biochemistry) biochem a polymer, consisting of polysaccharide and peptide chains, responsible for the structure of the cell wall of bacteria. Also called: murein
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
The human intestine hosts various species of bacterial assemblages called the intestine microbiota.4 Bacterial peptidoglycans, flagellins and other microbial metabolic by-products found in the intestines are known to worsen the clinical progression in patients with chronic liver diseases.
PGRPs are a family of pattern recognition receptors (PRRs) that bind to, and in some cases hydrolyze the peptidoglycans (PGNs) of bacterial cell walls (Nylund et al., 2017).
Bacteria cell walls contain large molecules called peptidoglycans which help maintain a cell's structural integrity and shape.
Peptidoglycans are similar pro-inflammatory substances derived from the outer cell wall of gram positive bacteria.
This electrostatic interaction might have the following two influences: (i) the external influence by promoting changes of permeation property of the microbial cell membrane hydrolysis of the peptidoglycans in the microbial cell envelope, leading to the leakage of proteinaceous and other intracellular constituents and (ii) the internal influence by CS penetrating into the cells and combining with microbial DNA or negatively charged cytoplasm, leading to distinct physiological derangements [27].
Bioaerosols may consist of pathogenic or non-pathogenic live or dead bacteria and fungi, viruses, high molecular weight allergens, bacterial endotoxins, mycotoxins, peptidoglycans, [beta] (1[right arrow]3)-glucans, pollen, plant fibers, etc., It is now appropriately recognized that exposures to biological agents in both the occupational and residential environment are associated with a wide range of adverse health effects with major public health impact, including contagious infectious diseases, acute toxic effects, allergies, and cancer.
The Gram-positive cell wall of lactic acid bacteria consists mainly of peptidoglycans, (lipo)teichoic acids, proteins, and polysaccharides [121].
Peptidoglycan composes the cell wall of bacterial cells and inhibitors of peptidoglycans form a major class of antibiotics.
In the bacterial peptidoglycan biosynthetic pathway, GlcNAc-MurNAc-pentapeptide monomer units synthesized in the cytoplasm are transferred to the periplasm and cross-linked to pre-existing peptidoglycans by penicillin-binding proteins (PBPs).
From the human health point of view, one of the most important cell wall components of bacterial origin are endotoxins and peptidoglycans [9].
Fosfomycin trometamol is a phosphonic acid derivative, which acts by inhibiting biosynthesis of peptidoglycans required for bacterial cell wall synthesis.
The diagnostic amino acids in cell wall peptidoglycans were re-analyzed and contained Lys-Asp (type A4a).