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The period of a woman's life characterized by physiological changes associated with the end of reproductive capacity, terminating with the completion of menopause. Also called climacteric.

per′i·men′o·paus′al adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Physiology) the period leading up to the menopause during which some of the symptoms associated with menopause may be experienced
ˌperiˌmenoˈpausal adj
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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The randomized, double-blind, placebo controlled study was conducted at Ham-Ming Hospital in Taiwan with 155 perimenopausal women.
Even more difficult to interpret are increased hCG concentrations in perimenopausal women who may or may not be pregnant, because the menopausal status of these women is often uncertain for both the clinician and the patient.
Her latest book, entitled Estrogen's Storm Season, written as a narrative, chronicles the lives of women and their particular perimenopausal problems under composite characterizations of her patients (although none of the stories is an exact medical profile).
Plus, the North American Menopause Society, in its most recent statement on the WHI released in September 2003, cautions that the effects of hormone therapy on the risk for breast cancer and osteoporotic fractures on perimenopausal women--the ones most likely to need hormone therapy for symptom relief--have not been established.
"Hyland's MenoCalm helps to relieve hot flashes and irritability in perimenopausal women without the side effects of conventional hormone replacement therapy."
Hildreth, M.D., from the University of Colorado School of Medicine in Aurora, and colleagues measured arterial stiffness, endothelial function, menopausal symptoms, depression, and quality of life (QOL) in 138 women classified as premenopausal (41 women), early or late perimenopausal (25 and 26 women, respectively), or early or late postmenopausal (22 and 24 women, respectively).
It divides menopausal staging into premenopausal (minor changes in cycle length particularly decreasing length of the cycle); early perimenopausal (irregular menses without skipping cycles and more than 7 days difference in length of consecutive cycle, experienced after the previously regular cycles); late perimenopausal (amenorrhea = 60 days but within past 12 months); and postmenopausal (no menstrual bleeding in the past 12 months).
The most probable aetiology of abnormal uterine bleeding is related to patient's reproductive age, whether the patient is premenopausal, perimenopausal or postmenopausal.
BOSTON -- Anti-Miillerian hormone levels strongly predict the rate of perimenopausal loss of bone mineral density and might help identify women who need early intervention to prevent future osteoporotic fractures, according to data from a review of 474 perimenopausal women that was presented at the annual meeting of the Endocrine Society.
Perimenopausal women (aged 50-54) had an increased prevalence of dyslipidemia, which can elevate the risk of AMI.
Effect of medroxyprogesterone on depressive symptoms in depressed and nondepressed perimenopausal and postmenopausal women after discontinuation of transdermal estradiol therapy.
"If our findings in rats translate to humans, it means that the perimenopausal period is a critical window of time for determining breast cancer risk later in life," MacLean said.