* Supplements used to help prevent migraine include the root of Petasites hybridus
(butterbur), magnesium, vitamin B2 (riboflavin), Tanacetum parthenium (feverfew), and coenzyme Q10.
Small studies have suggested that the root of the butterbur plant, Petasites hybridus
, can decrease migraine frequency, but the plant can be toxic to the liver and, in animal studies, has led to genetic changes that could lead to cancer.
Butterbur root: Butterbur (Petasites hybridus
) extracts possess analgesic, anti-inflammatory, antispasmodic properties (Pothmann 2005; Oelkers-Ax 2008).
Toxicogenomics applied to cultures of human hepatocytes enabled an identification of novel petasites hybridus
extracts for the treatment of migraine with improved hepatobiliary safety.
ydi'r enw gwyddonol ar yr alan mawr a Butterbur yn Saesneg ac mae'n blodeuo rhwng mis Mawrth a mis Mai.
Nevertheless, at least two surveys include Petasites hybridus
, Eupatorium cannabinum and Cirsium oleraceum and can be ascribed to the subassociation petasitetosum hybridi Oriolo & Poldini 2002 typical of a mesophylous mesophilous environment.
Mae'n bur debyg eich bod wedi sylwi ar ddail yr alan mawr (Petasites hybridus
; butterbur) ym mn y cloddiau erbyn hyn.
Similar findings have been reported for some species like Petasites hybridus
(Wildi et al., 1998) , Eucalyptus grandis (Luis et al., 1999)  and Hybanthus enneaspermus (Prakash et al., 1999) .
Clinical studies from Germany have positively confirmed that an herbal extract known as butterbur (Petasites hybridus
) may cut the frequency of migraine headaches by up to 50% in long-term migraine sufferers.