The generics and their branded versions are citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil, Paxil CR, Pexeva
), and sertraline (Zoloft).
Brisdelle and Pexeva
are marketed by Noven Therapeutics.
Recent research has associated increased risk for memory loss with certain antidepressants used to treat major depressive disorder, including selective serotonin reuptake inhibitors, like Prozac, Paxil and Pexeva
, and serotonin/norepinephrine reuptake inhibitors, like Effexor; older as well as newer anticonvulsants, such as Neurontin, Lamictal, Keppra, Lyrica, and Topamax used to treat neuropathic pain, epileptic seizures, and bipolar disorder; and benzodiazepine-like hypnotics, including Ambien, used for anxiety, insomnia, and sleep problems.
"All medications that are approved for treating depression, including Paxil and Pexeva
, have a boxed warning about an increased risk of suicide in children and young adults.
The active ingredient of the newly approved Brisdelle, made by Miami's Noven Pharmaceuticals Inc., an American subsidiary of Japan's Hisamitsu Pharmaceutical Co., is a selective serotonin reuptake inhibitor, or SSRI, called paroxetine -- the same as anti-depressant medications Paxil and Pexeva
(another Noven-made medication).
Noven Therapeutics currently promotes the oral prescription products Pexeva
, Stavzor and Lithobid to psychiatrists and other appropriate physicians in the US.