phagosome

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Related to Phagosomes: phagolysosome

phag·o·some

 (făg′ə-sōm′)
n.
A membrane-bound vesicle that is formed inside a cell by an inward folding of the cell membrane and that contains extracellular material ingested by phagocytosis.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

phagosome

(ˈfæɡəʊsəm)
n
(Biology) biology a cavity or area within a cell in which matter is retained in the process of phagocytosis
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

phag•o•some

(ˈfæg əˌsoʊm)

n.
a vacuole that contains the ingested matter of a phagocytic cell.
[1955–60]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive ?
'We then found an older study, from 2004, which showed that the fusion between phagosomes and lysosomes is blocked by these two enzymes.
In macrophages, the infectious agent is degraded within the phagosomes, and components of the pathogen are presented to the cells involved in the adaptive immune response [17].
Drosophila mauve mutants reveal a role of LYST homologs late in the maturation of phagosomes and autophagosomes.
Autophagy may be involved in the removal of pathogens that enter the cytoplasm through the cell membrane or through phagosomes, suggesting that a bacterial infection may activate autophagy [17].
Membrane vesicles shed by Legionella pneumophila inhibit fusion of phagosomes with lysosomes.
fumigatus conidia, activates LAP via a Dectin-1/Src/Syk kinase signaling cascade and subsequent lipidate LC3 (LC3-II) recruitment to Aspergillus-containing phagosomes [19].
In addition, they performed Western blot and confocal microscopy experiments, where it was observed that simvastatin promotes maturation in phagosomes and autophagy in macrophages infected by M.
abortus 2308 for phagosome-lysosome fusion in RAW264.7 murine macrophages, 9% of Green Fluorescence-labelled phagosomes colocalized with lysosome at 4 h post-infection.
[7] The antimicrobial peptide, Cathelicidin is directly up-regulated by 1, 25[(OH).sub.2]D [8-9] which helps in phagocytosis of Mtb followed by fusion of phagosomes with lysosomes to form autolysosomes and expression of lysosomal enzymes and reactive oxygen species.
These mineralized bodies range in diameter from 5 mm to 10 mm, look like owl eyes or ring particles and are present in intact histiocyte phagosomes. Ultrastructurally, they are composed of concentric crystalline laminations with a thick inner zone and a fine outer zone.