phenobarbital

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phe·no·bar·bi·tal

 (fē′nō-bär′bĭ-tôl′, -tăl′)
n.
A long-acting barbiturate, C12H12N2O3, used medicinally as a sedative, hypnotic, and anticonvulsant, sometimes in the form of its sodium salt.

phenobarbital

(ˌfiːnəʊˈbɑːbɪtəl) or

phenobarbitone

n
(Pharmacology) a white crystalline derivative of barbituric acid used as a sedative for treating insomnia and as an anticonvulsant in epilepsy. Formula: C12H12N2O3

phe•no•bar•bi•tal

(ˌfi noʊˈbɑr bɪˌtɔl, -ˌtæl, -nə-)

n.
a white, crystalline powder, C12H12N2O3, used as a sedative, a hypnotic, and as an antispasmodic in epilepsy.
[1915–20]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.phenobarbital - a long-acting barbiturate used as a sedative
barbiturate - organic compound having powerful soporific effect; overdose can be fatal
Translations

phe·no·bar·bi·tal

n. fenobarbital, hipnótico, sedante, nombre comercial Luminal.

phenobarbital

n fenobarbital m
References in periodicals archive ?
Comparative study on glutathione transferases of rat brain and testis under the stress of phenobarbitol and [beta]-methylcholanthrene.
Reported analytes include assays for avidin-biotin immunoradiometric testing (thyrotropin, prolactin, HCG), triidothyronine, vitamin B12, C-reactive protein, various drugs (phenytoin, phenobarbitol, carbamazepine, quinidine, and lidocaine), myoglobin, CK-MB, and glucose.
*** Medications: corticosteroids (prednisone, prednisolone, cortisone and dexa-methasone), glucocorticoids (decrease blood levels of hormones), anticonvulsants (phenobarbitol, phenytoin and carbamaze-pine/liver conversion vitamin D), thyroid meds (levothroid, levoxyl and synthroid), diuretics (furosemide, bumetanide, etha-crynic acid and torsemide), and blood thinners (heparin and Coumadin)
phenobarbitol phenytoin carbamazepine rifampicin antiretrovirals were excluded from the study.
* Multiple drug interactions including (but NOT limited to) psychiatric medications, calcium channel blockers, digoxin, cholesterol-lowering agents, warfarin, antifungals, antibiotics, felbamate, INH, topiramate, carbamazepine, phenobarbitol and vigabatrin
If an inducer of these UGTs (eg, rifampin, phenytoin, phenobarbitol, ritonavir) must be co-administered with INVOKANA[TM] (canagliflozin), consider increasing the dose to 300 mg once daily if patients are currently tolerating INVOKANA[TM] 100 mg once daily, have an eGFR greater than 60mL/min/1.73[m.sup.2], and require additional glycemic control.
Lipase inhibitors such as Orlistat and cholestyramine may reduce its absorption, and phenobarbitol and phenytoin may increase the hepatic metabolism of vitamin D to inactive compounds and thereby decrease calcium absorption.
PCBs were grouped as follows: group 1, potentially estrogenic and weak phenobarbitol inducers (congeners 44, 49, 52, 101, 187, 174, 177, 157/201); group 2, potentially antiestrogenic and dioxin-like (congeners 95/66, 74, 77/110, 105/141, 118, 156, 167, 128, 138, 170); and group 3, phenobarbital, cytochrome P450 (CYP)1A, and CYP2B inducers (congeners 99, 153, 180, 196/203, 183).
The MIA seized ten pills of MDMA-ecstasy, a number of pills of phenobarbitol weighing 8.1 g, and over 286 kg of acetic acid, which can be converted to acetic anhydride.