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n.1.(Chem.) A glucoside extracted from Phillyrea as a bitter white crystalline substance. It is sometimes used as a febrifuge.
Webster's Revised Unabridged Dictionary, published 1913 by G. & C. Merriam Co.
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Furthermore, [beta]-sitoserol (1), phillygenin (4), mannitol (6), verbascoside (10) and phillyrin (12) were isolated from this species for the first time.
Compound pH-based Rule-based ionization ionization Stigmasterol (2) -36.77 -35.48 (+)-Epieudesmin (3) -36.44 -36.04 Phillygenin (4) -35.19 -35.87 Prunasin (5) -29.05 30.00 Pinoresinol-4-0-[beta]-D-glucoyranoside (7) -42.34 -42.82 Leucoseptoside A (8) -52.87 -48.52 Martynoside (9) -52.97 -50.96 Verbascoside (10) -48.44 -52.21 Campneoside II (11) -50.71 -51.25 Phillyrin (12) -47.21 -49.15 Pinoresinol-4-0-[6"-0-(E)-feruloy)]-[beta]- -56.18 -53.48 D-glucopyranoside (13) 6,7-dimethyl-3-|(methyl(2-|methyl((1-(3- -45.74 -44.97 (trifluoromethyl)phenyl|-1H-indol-3-yl) methyl)amino|ethyl)methyl]-4H-chromen-4- one.
However, this result was special, and the same circumstance was found for ultrasound-assisted extraction of phillyrin from Forsythia suspensa [26].
Li, "Ultrasound-assisted extraction of phillyrin from Forsythia suspensa," Ultrasonics Sonochemistry, vol.
Li, "Ultrasound-assisted extraction of phillyrin from Forsythia suspensa, " Ultrasonics Sonochemistry, vol.
Phenylethanoid glycosides like forsythoside A, forsythoside B, and lignans such as phillyrin, forsythialan A, forsythialan B, phillygenin, and 8-hydroxypinoresinol were reported as antioxidant components of FSE (Piao et al., 2008a ; Qu et al., 2008).
The lignans are phillyrin, pinoresinol-[beta]-D-glucoside, pinoresinol-di-[beta]-D-glucoside, phillyrin-2-O-[beta]-D-glucoside and phillyrin-6-O-[beta]-D-glucoside, with the secoiridoids reported to be oleuropein, ligustroside and angustifolioside B.
The presence of phillyrin in the stem bark of fringe tree was reported by Steinegger in 1959.
1) were about 8.036, 1.356 and 0.8270 mg/ml, respectively, higher largely than that of lignans, such as pinoresinol-p-D-glucoside, arctiin, phillyrin and arctigenin (Fig.
Isoforsythoside (98% pure), rutin, quercetin, pinoresinol-[beta]-D-glucoside, arctiin and phillyrin were purchased from Chengdu Herbpurify Co., Ltd.
Besides, the contents of phillyrin, pinoresinol glucoside and phillygenin, the representative ingredients in lignans of weeping forsythia extract, were about 0.7%, 0.5% and 0.15%, respectively, lower than that of caffeyol glycosides such as FTA.
In our previous study, we found that ETA instead of phillyrin in weeping forsythia extract was survived good positive correlation between dose and effects of antibacterial, antioxidant and antiviral activities via pharmacokinetic/pharmacodynamic (PK/PD) model combined with PLS (partial least squares), and the antibacterial, antioxidant and antiviral effects were improved as the content of FTA in weeping forsythia extract was enhanced, and showing obvious correlation between dose of FTA and pharmacological effects.