Phloretin


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Related to Phloretin: ferulic acid

Phlor´e`tin


n.1.(Chem.) A bitter white crystalline substance obtained by the decomposition of phlorizin, and formerly used to some extent as a substitute for quinine.
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Phloretin was dissolved in dimethyl sulfoxide (DMSO) for live culture with cells; a final culture concentration of DMSO was <0.5%.
Beauty Ingredients: natural phloretin 98%; natural caffeine; willow bark extract; cordyceps extract; COQ10 WS; Biolut lutein esters; natural extracts; natural powders; natural colors; natural sweeteners
Apple flavonoid phloretin inhibits Escherichia coli O157:H7 biofilm formation and ameliorates colon inflammation in rats.
Oral and topical ingredients include botanical plant extracts, green tea polyphenols, an turmeric, algae extracts, quercetine, sily-marin, phloretin Flavanoids, pomegranate, blueberry, herbs and spices, as well as alpha-lipoic acid, aspirin, B vitamins, aminoguanidine, pyridoxamine and carnosine.
Appjfnol[R] (including apple phloretin, phloridzin, polyphenol, chlorogenic acid etc)
Additional support for the protective effects of antioxidants against environmental insults was determined in the early 21st century with the Findings that the combination of vitamin C, ferulic acid (Fig.3) and phloretin substantially decrease ultraviolet-induced photodamage.
For example, synthetic 7-carbosymethoxy-3',4',5-trimethoxyflavone enhances the migration of gastric epithelial cells (Kim et al., 2012), a mixture of resveratrol, ferulic acid, phloretin, and tetrahydrocurcuminoid promotes fibroblast migration (San Miguel et al., 2011), 7-hydroxy-4'-methoxyisoflavone (formononetin) enhances the migration of wounded endothelial cells (Huh et al., 2011), and anthocyanins stimulate the migration of human keratinocytes (Nizamutdinova et al., 2009).
Curcumin is structurally related to the classic glucose transport inhibitor, phloretin (see Discussion section).
Beauty Ingredients: Natural phloretin 98%, natural caffeine, willow bark extract, cordy-ceps extract, COQ10 WS, Biolut lutein esters, natural extracts, natural powders, natural colors, natural sweeteners
This idea is supported by studies reporting that phloridzin, the 2'-0-glucoside of phloretin, has anti-diabetic properties (DimitraKoudis et al., 1992; Najafian et al., 2012; Rastogi et al., 1997; Rossetti et al.,1987).
In addition, a number of ingredients are important antioxidants including: Lycopene, ferulic acid, niacinamide (nicotinamide), coenzyme Q (ubiquinone), idebenone, silymarin, quercitin, genisten., phloretin, oryzanol, curcumin, turmeric, oleuropein and resveratrol.
Application of directly coupled HPLC-NMR-MS to the identification and confirmation of quercetin glycosides and phloretin glycosides in apple peel.