phlorizin


Also found in: Medical, Encyclopedia, Wikipedia.

phlorizin

(ˈflɒrɪzɪn; flɒˈraɪzɪn)
n
(Chemistry) chem a bitter chemical found in the bark of certain fruit tree roots
Mentioned in ?
References in periodicals archive ?
Effects of hyperglycemia on glucose transporters of the muscle: Use of the renal glucose reabsorption inhibitor phlorizin to control glycemia.
In this work, the chemical components of the sweeteners isolated from Sweet Tea were identified as 3-hydroxy phlorizin (1), phlorizin (2), kaempferol-3-O-[beta]-D-glucoside (3) and trilobatin (4) by ESI*-MS and NMR analyses.
The glucose or sucralose inhibition appears to be reversed by T1R2/3 antagonists lactisole [10, 55] and amiloride [56], but not by inhibitors of glucose transporters such as phloretin and phlorizin [53].
Other glucose-lowering agents such as cathelicidin antimicrobial peptide [71], phlorizin [72], and transglucosidase [73] were also proven to have beneficial modulatory effects on gut microbiota composition, glucose homeostasis, insulin resistance, and [beta] cell function.
After intake, the processes of hydrolysis occur, but since the union-[beta] in these sugars is resistant to the hydrolysis produced by pancreatic enzymes, this metabolic process occurs in the intestinal lumen through actions of the lactase phlorizin hydrolase that is located in the membrane of enterocytes.
Tadaki et al., "Contribution of hyperglycemia on diabetic complications in obese type 2 diabetic SDT fatty rats: effects of SGLT inhibitor phlorizin," Experimental Animals, vol.
In addition, current methods for luminal degradation do not include the activity of brush border enzymes such as lactase phlorizin hydrolase (LPH) (Day et al., 2003).
Gold, "Phlorizin enhancement of memory in rats and mice," Pharmacology, Biochemistry and Behavior, vol.
Gao et al., "P38 and JNK signal pathways are involved in the regulation of phlorizin against UVB-induced skin damage," Experimental Dermatology, vol.
Ferulic acid (FA), cynaroside (Cyn), ursolic acid (UA), gallic acid (Gal), protocatechualdehyde (Pal), protocatechuic acid (Pac), luteolin (Lut), rutin (Rut), epicatechin gallate (ECG), naringenin-4-O-b-D-glucopyranoside (Nar), phlorizin (Phl), chrysophanol (Chr), emodin (Emo), physcion (Phy), catechin (Cat) were isolated from the extract as previously described [26].
Zhang et al., "Beneficial effects of phlorizin on diabetic nephropathy in diabetic db/db mice," Journal of Diabetes and Its Complications, vol.