phosphodiester bond

(redirected from Phosphoester)
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phos·pho·di·es·ter bond

A covalent chemical bond that links two carbon atoms through a phosphate group, especially the bonds that link the pentose sugars of adjacent nucleotides in polynucleotide chains of RNA and DNA.

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They degrade into nontoxic products through hydrolysis and enzymatic cleavage of their phosphoester bonds under physiological conditions [22, 24].
Phosphorylation occurs predominantly on serine, threonine, and tyrosine side chains or residues through a phosphoester bond formation; this constitutes approximately 86.4%, 11.8%, and 1.8%, respectively, of the human phosphor-proteome [123].
2 to understand why linking rna monomers with phosphoester bonds is so difficult, To understand the molecular mechanism of possible catalysts and to suggest key improvements.
All PLDs contain two HKD motifs and conserved amino acid residues (His, Lys, and Asp) form a catalytic triad responsible for the hydrolysis of phosphoester bonds [25].
Organophosphates compounds are composed of three phosphoester linkages and the phosphorus is also oxygen or sulfur by double bond thus, the breakdown of these linkages could be the way to degrade the organophosphorus compounds and the esterase could be responsible enzyme for it (29, 19).
Nonspecific phosphatases are known to perform dephosphorylation of phosphoester or phosphoanhydride bonds in organic matter [27].

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