Began dosing patients in the Companys Phase 1 clinical trial of IMGN632, a CD123-targeting ADC integrating a potent DNA-alkylating payload intended to treat a range of hematological malignancies, including AML and blastic plasmacytoid dendritic cell
neoplasm (BPDCN); and
Frequency and molecular expression of plasmacytoid dendritic cell
s (NASDAQ: IMGN) investigational new drug application for IMGN632 in patients with CD123-positive hematological malignancies, including acute myeloid leukemia (AML) and blastic plasmacytoid dendritic cell
neoplasm (BPDCN), the company said.
CD123, the plasmacytoid dendritic cell
phenotypic marker is abundant in leprosy type 1 reaction.
2012) Constitutive plasmacytoid dendritic cell
migration to the splenic white pulp is cooperatively regulated by CCR7- and CXCR4-mediated signaling.
Dendritic cells (DCs) are the most important antigenpresenting cells, and are divided into myeloid dendritic cells (mDC) and plasmacytoid dendritic cell
Patients with blastic plasmacytoid dendritic cell
neoplasms, previously known as blastic NK-cell tumors or [CD4.
Gilliet M, Conrad C, Geiges M, et al: Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell
National Library of Medicine) with the following keyword "blastic plasmacytoid dendritic cell
It was reported yesterday that the collaboration is aimed at accelerating the development of SL-401 for the treatment of acute myeloid leukemia and blastic plasmacytoid dendritic cell
neoplasm, a rare haematological disorder with both leukemic and lymphomatous characteristics.
Food and Drug Administration (FDA) for the treatment of blastic plasmacytoid dendritic cell
neoplasm (BPDCN), a rare and aggressive hematologic malignancy for which there is no effective treatment.
Early plasmacytoid dendritic cell
changes predict plasma HIV load rebound during primary infection.