10,370,452 covering compositions and uses of effector T cells expressing a chimeric antigen receptor, where such T cells are derived from a pluripotent stem cell
including an induced pluripotent stem cell
VANCOUVER, B.C., January 23, 2019 -- StemCell Technologies has released mTeSR Plus, an enhanced version of mTeSR1, a feeder-free human pluripotent stem cell
(hPSC) maintenance medium.
"Once we create genetically edited pluripotent stem cell
lines that can produce tumor-specific T cells in artificial thymic organoids, we can expand those stem cell lines indefinitely," said Amelie Montel-Hagen, the study's first co-author.
Pictures were also taken daily using the Leica DV100 digital camera attached to the inverted Leica DMR fluorescent microscope (Leica, Switzerland) in order to evaluate the morphological alterations in the pluripotent stem cell
colonies during the differentiation process.
INTRODUCTION: Induced pluripotent stem cells
(Also known as iPS cells or iPSCs) are a type of pluripotent stem cell
that can be generated directly from adult cells.
Topics include engineering the pluripotent stem cell
niche for directed mesoderm differentiation, cell mechanobiology in regenerative medicine, systems-engineering principles in signal transduction and cell-fate choice, biomaterial scaffolds for human embryonic stem cell culture and differentiation, stem cells and regenerative medicine in the nervous system, stem cells and regenerative medicine for treating damaged myocardium, synthetic biomaterials and stem cells for connective tissue engineering, and derivation and expansion of human pluripotent stem cells
However, in line with the WARF decision, if the pluripotent stem cell
is removed at some stage in the development of the human body, and the removal results in the destruction of that stage of the human body, the pluripotent stem cell
is not patentable.
Smuga-Otto et al., "Induced pluripotent stem cell
lines derived from human somatic cells," Science, vol.
The project's focus is to genetically engineer the firm's CyT49 pluripotent stem cell
Summary: TEHRAN (FNA)- Researchers developed a new type of human pluripotent stem cell
that can be manipulated more readily than currently available stem cells.
SAN DIEGO, Calif., July 24, 2018 -- University researchers have examined the whole genome sequences of 18 induced pluripotent stem cell
(iPSC) lines derived from skin cells that they had reprogrammed to identify and characterize somatic mutations.
Editing the pluripotent stem cell
genome relies heavily on the survival of single cells to establish clonal cell lines.