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Any of various mainly toxic antibiotics derived from strains of the soil bacterium Bacillus polymyxa and used to treat various infections with gram-negative bacteria.

[New Latin polymyxa, specific epithet (poly- + Greek muxa, slime) + -in.]


(Pharmacology) any of several polypeptide antibiotics active against Gram-negative bacteria, obtained from the soil bacterium Bacillus polymyxa
[C20: from New Latin Bacillus polymyxa; see poly-, myxo-, -in]
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Noun1.polymyxin - any of several toxic antibiotics obtained from a particular soil bacterium
antibiotic, antibiotic drug - a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs"
References in periodicals archive ?
Tenders are invited for Oint Polymixin B Sulphate Plus Bacitracin Zinc Plus Neomycin Sulphate
Successfully isolated [beta]-hemolytic colonies were subjected to a series of tests to confirm traits characteristic of MRSA including Gram staining for G(+) cocci cluster morphology, positive assay results for catalase and coagulase production (both tube and slide for the latter), and antibiotic resistance in the presence of polymixin B.
Prior use of antibiotics along with their duration of use was documented, including for vancomycin, teicoplanain, carbapenems, piperacillin, tazobactam, quinolones, third- generation cephalosporins, penicillin, metronidazole, polymixin and colistin.
The group I was treated as control group and antiseptic dressing of surgical wound was carried out with Povidone iodine and local application of Polymixin B sulphate, Neomycin sulphate and Zinc Bacitracin ointment, Inj.
Fosfomycin, tigecycline, polymyxin B, and colistin are the last-line-of-defense therapies against CRGNBs, but some bacteria are resistant to fosfomycin; polymixin B has limited therapeutic scope; some carbapenem-resistant bacteria are also intrinsically resistant to colistin; and there have been reports recently of tigecycline-related and polymxin B-related deaths.
Many drugs like aspirin, NSAIDs, Polymixin B, ACE inhibitors etc.
Its resistance to colistin - a polymixin drug of last resort - is likely to quickly render this drug ineffective.
In Europe, 80 percent of polymixin sales -- mainly colistin -- are in Spain, Germany and Italy, according to the European Medicines Agency's Surveillance of Veterinary Antimicrobial Consumption (ESVAC) report.
Amikacin, Ampicillin, Amoxycillin/Clavalanic acid, Ceftazidime, Ceftazidime/Clavulanic acid, Ceftriaxone, Cefuroxime, Cefotaxime, Chloramphenicol, Ciprofloxacin, Co-trimoxazole, Gentamycin, Imipenem, Meropenem, Ofloxacin, Ticarcillin/Clavalanic acid, Piperacillin, Piperacillin/Tazobactam, Colistin, Polymixin B, Tigecycline.
In swimmers with Grommets, polymixin B plus neomycin and hydrocortisone (PBNH) two drops after swimming, may decrease rate of otorrhea.