potentiator


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potentiator

(pəˈtɛnʃɪˌeɪtə)
n
(Medicine) a reactant or reagent that enhances the action of a drug
References in periodicals archive ?
* A Phase 2 dose-ranging study is ongoing to evaluate the once-daily potentiator VX-561 to support potential Phase 3 development of VX-561 in a once-daily triple combination regimen.
The funding will support the further clinical development of SPR206, Spero's intravenous-administered product candidate from its Potentiator Platform that is being developed as an innovative alternative option to treat MDR Gram-negative bacterial infections.
The results were confirmed by sequencing of the mip- (macrophage infectivity potentiator) gene from L.
Rheumatoid factor as a potentiator of anti-citrullinated protein antibodymediated inflammation in rheumatoid arthritis.
A CFTR potentiator in patients with cystic fibrosis and the G551D mutation.
This evidence supports chitosan as a robust immune potentiator for mucosal vaccination.
Including the normative dimension of moral responsibility to sustaining life, and the aesthetic dimension of a relationship with nature, however, reveals waste as a cyclogical potentiator of vitality, thereby identifying potential emancipation and reconciliation of our Lifeworlds in those very forces which simultaneously repress and alienate us.
Bcl-3 induced by IL-22 via STAT3 activation acts as a potentiator of psoriasis-related gene expression in epidermal keratinocytes.
Studies with monotherapies of either ivacaftor (potentiator) or lumacaftor (corrector) have shown little success in these patients (68).
The firm's proprietary triple combination includes a novel cystic fibrosis transmembrane conductance regulator amplifier, third generation corrector and potentiator, called PTI-428, PTI-801 and PTI-808, respectively.
(NYSE: PFE) PF-04958242, a first-in-class, Phase 2b ready AMPA receptor potentiator for cognitive impairment associated with schizophrenia, the company said.
Conference highlights include how GARDP are facilitating the research and development of new antibiotics, The Pew Charitable Trusts discussing SPARK; a digital platform where researchers can share data, ideas and insights to aid new antibiotic discovery, and how Oppliotech is using a systems biology approach to develop anti-bacterials via a computational network model to help identify potentiator targets.