transmissible spongiform encephalopathy

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Related to Prion diseases: Gerstmann-Straussler-Scheinker syndrome

transmissible spongiform encephalopathy

n. Abbr. TSE
Any of a group of neurodegenerative diseases of humans and other animals, including scrapie, bovine spongiform encephalopathy, and Creutzfeldt-Jakob disease, that are thought to be caused by prions and can be transmitted by contact from one individual to another.

transmissible spongiform encephalopathy

n
(Veterinary Science) the full name for TSE

transmis′sible spon′giform encephalop′athy


n.
any of several encephalopathies, including bovine spongiform encephalopathy, scrapie, and kuru, characterized by spongy degeneration of brain tissue and believed to result from the ingestion of a toxic protein or virus.
[1990–95]
Translations
overførbare svampeagtige hjernesygdomme
übertragbare spongiforme Enzephalopathie
encefalopatía spongiforma transmisible
tarttuva sienimäinen aivosairaus
encefalopatia spongiforma transmissibile
zakaźna encefalopatia gąbczasta
References in periodicals archive ?
Familial human prion diseases are passed within families and are associated with 34 known prion protein mutations.
Experts say this marks a significant milestone in quest to better understand prion diseases in people, and could eventually aid the development of new therapies.
The field has grown so much since the 2004 second edition of Prion Biology and Diseases that Prusiner decided to split this edition into two volumes, this one devoted primarily to prion biology, with an emphasis on functional or physiological prions, but also with an overview of prion diseases.
The pathogenesis of these fatal transmissible spongiform encephalopathies (TSEs), called prion diseases, is associated with the accumulation of the abnormal isoform ([PrP.
In the case of those rugby players and others who may have more secretively consumed human meat in recent decades, it can't be known definitively whether they will be safe from the same kuru disease the Fore tribe experienced, as prion diseases have long incubation periods, sometimes even decades long.
This is a prion disease found in deer and elk that is similar to other prion diseases such as Mad Cow in cattle (that humans can get), and Creutzfeldt-Jakob Disease (found only in humans).
About 10 to 15 percent of prion diseases are caused by a mutation in the PRNP gene, leading to such deadly diseases as Creutzfeldt-Jakob disease, Gerstmann-Straussler-Scheinker syndrome and fatal familial insomnia, the disease that killed Vallabh's mother.
Cunningham, "Mouse behavioural studies and what they can teach us about prion diseases," in Neurodegeneration and Prion Disease, D.
Dr Lasmezas, a professor at The Scripps Research Institute for the past ten years, is also a multiple TED speaker, with focus on how misfolded proteins lead to neuronal dysfunction and loss in diseases including Alzheimer's, Parkinson's and prion diseases.
Prion diseases are transmissible neurodegenerative disorders with different etiologies as they can be sporadic, genetic or acquired by infection (1,2).
Daniel Gajdusek, Michale Alpers, and Baruch Blumberg won the Nobel Prize in Medicine in 1976 for their research demonstrating prion diseases were infectious across species, so this is of great concern to humans.
This exciting advance, the culmination of decades of studies on prion diseases, markedly improves on available diagnostic tests for CJD that are less reliable, more difficult for patients to tolerate, and require more time to obtain results," says Anthony S.