proband

(redirected from Probands)
Also found in: Medical, Encyclopedia, Wikipedia.

pro·band

 (prō′bănd′, prō-bănd′)
[German Proband, person being tested, test subject, from Latin probandus, gerundive of probāre, to test; see prove.]

proband

(ˈprəʊbænd)
n
(Medicine) another name (esp US) for propositus2
[C20: from Latin probandus, gerundive of probāre to test]
Mentioned in ?
References in periodicals archive ?
(2) Targeted NGS of 159 known deafness genes identified p.G141R as the only likely pathogenic mutation in probands of both families (Supplementary Table 2).
Loeys et al., "Effect of mutation type and location on clinical outcome in 1,013 probands with Marfan syndrome or related phenotypes and FBN1 mutations: an international study," The American Journal of Human Genetics, vol.
(2) First-degree family members (parents, children, and siblings) of FIPA probands should be offered genetic testing for their familial AIP mutation following genetic counselling.
Here, we report previously undescribed funduscopic, fundus autofluorescence (FAF), infrared imaging, fluorescein angiography (FA), and SDOCT abnormalities in three probands with PCD.
identified rare variants of LZTR1 using whole-exome sequencing in 6/50 Brazilian probands (p.G248R, p.
In this study, we characterize the spectrum of mutations causing FH in 40 Turkish probands suspected to have FH.
Blood was collected from the probands and their family members; subjects were examined by CT testing and B ultrasonic testing.
The probands are a phenotypically normal consanguineous couple who were referred to Center for Comprehensive Genetics Services in summer 2015 because of their history of 4 consecutive first trimester fetal loss.
All the probands studied were compared with respect to their parental education, occupation, religion, presence of consanguineous relationship in parents and degree of consanguinity and accordingly classification of probands was done.
"Probands with chronic migraine and their spouses perceive a higher rate of burden on children," Dr.
The authors first established maternal haplotypes and identified the mutated haplotype from 4 DMD pregnant carrier female carriers and the respective probands. The major challenge of this application was the ability to detect haplotype dosage imbalance in the small amount of fetal DNA in the plasma from the mothers.