propofol


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pro·po·fol

 (prō′pō-fôl′, -fōl′)
n.
A rapidly acting sedative and hypnotic drug, C12H18O, administered intravenously to induce and maintain anesthesia or sedation.

[prop(yl) + alteration of ph(en)ol.]
References in periodicals archive ?
We examined protective effects and mechanism of propofol against H/R-induced injury in HBVSMC in the presence or absence of SP600125/Everolimus.
The family of one Bootle teenager believe their loved one would still be alive today if he had been given a smaller dose of an anaesthetic called propofol.
Propofol is the most commonly used induction agent, as it has rapid onset and early recovery due to short half-life and rapid elimination from the blood circulation.
Objective: To investigate the Clinical practice value of nitrous oxide inhalation and intravenous propofol and midazolam sedation in transnasal gastroscopy.
Background: Propofol is increasingly used during partial support mechanical ventilation such as pressure support ventilation (PSV) in postoperative patients.
Since its introduction in 1986, propofol (2, 6-diisopropylphenol), a sedative-hypnotic agent chemically distinct from other intravenous induction agents, has been used for the induction and maintenance of general anesthesia and"conscious sedation" in greater than 80% of cases, virtually replacing sodium thiopental and all other short-ac ting barbiturates as induction agents.
Group II received ketofol, a 1:1 mixture of ketamine 10 mg/mL and propofol 10 mg/mL, in a single syringe intravenously at a dose of 0.
Objective: To evaluate the optimal effect-site concentration (Ce) of propofol during endotracheal suction (ETS) in the postoperative Intensive Care Unit (ICU) sedated patients.
There are various pharmacokinetic models for the use of propofol in TCI (Marsh, Schnider and Schuttler, (2) among others) while manual infusion can be carried out with or without an initial bolus, though with no bolus it takes a long time to achieve the desired hypnotic effect (approximately 4 or 5 half-lives).
Contract awarded for Convention Propofol Tiva Pediatrica
Objective: To determine the frequency of Propofol associated pain in patients undergoing general anaesthesia using lignocaine alone and metoclopramide given prior to lignocaine.
Globally, propofol is the most frequently used intravenous (IV) anesthetic for the induction and maintenance of general anesthesia (1).