cyclooxygenase

(redirected from Prostaglandin-endoperoxide synthase)
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Related to Prostaglandin-endoperoxide synthase: COX1

cy·clo·ox·y·gen·ase

 (sī′klō-ŏk′sĭ-jə-nās′, -nāz′)
n.
1. See COX-1.
2. See COX-2.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cyclooxygenase - either of two related enzymes that control the production of prostaglandins and are blocked by aspirin
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Cox-1, cyclooxygenase-1 - an enzyme that regulates prostaglandins that are important for the health of the stomach lining and kidneys; "an unfortunate side effect of NSAIDs is that they block Cox-1"
Cox-2, cyclooxygenase-2 - an enzyme that makes prostaglandins that cause inflammation and pain and fever; "the beneficial effects of NSAIDs result from their ability to block Cox-2"
References in periodicals archive ?
1994) Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2.
1994) The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells.