psoralen

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pso·ra·len

(sôr′ə-lən)

Any of a group of chemical compounds found in certain plants, used to treat psoriasis and vitiligo.

[From New Latin Psōralea, plant genus, from Greek psōralea, neuter pl. of psōraleos, mangy (from the appearance of the plants' leaves), from psōrā, itch.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

psoralen

(ˈsɔːrəˌlɛn)

(Pharmacology) any of various naturally occurring photoreactive chemicals, found in some plants, some of which are used in the treatment of skin disorders such as psoriasis and vitiligo.

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

Translations

psoralen

n psoraleno; — plus ultraviolet A (PUVA) psoraleno más luz ultravioleta A

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References in periodicals archive ?

The damage types include photoproducts--pyrimidine dimers, intra-strand bonds, large adducts resulting from exposure to aflatoxin, benzopyrene, psoralens, or polycyclic aromatic hydrocarbons.

Oxidative stress--repair systems of oxidatively damaged biomolecules

However, the fresh root contains psoralens that are known to promote tumours.

Plant of the Week: Plant thought to offer protection against evil spirits

A range of novel PRTs for blood products that involve the combined use of ultraviolet light and reagents such as psoralens or riboflavin are available (35,36).

Japanese Encephalitis Virus Transmitted Via Blood Transfusion, Hong Kong, China

The treatment includes topical substances (corticosteroids, immunomodulators, UV exposure, lasers, etc.), combined with systemic substances (psoralens, antioxidants); there are also other additional controversial treatments (Bologna et al 2012; Griffiths et al 2016).

Vitiligo; or, the dubious attraction of the uncanny

The drugs which are often associated with photosensitivity reactions are NSAIDs (e.g., ibuprofen, ketoprofen, piroxicam, diclofenac), cardiovascular drugs (furosemide, amiodarone, thiazides), antibiotics (tetracyclines, ciprofloxacin, sulfonamides), psoralens, neuroleptic drugs such as phenothiazines (especially chlorpromazine), oral contraceptives, retinoids (isotretinoin, acitretin), antifungals, etc.

DRUG-INDUCED PHOTOSENSITIVITY--A CONTINUING DIAGNOSTIC CHALLENGE

Vitiligo and psoralens. Oxford: Pergamon Press 1968.

A study on clinical patterns of Vitiligo and its associated diseases in patients attending dermatology clinic at a tertiary level care centre

Bennett, "Bullous pemphigoid: occurrence in psoriasis treated with psoralens plus long-wave ultraviolet radiation," Archives of Dermatology, vol.

PUVA Induced Bullous Pemphigoid in a Patient with Mycosis Fungoides

However, CPEOs are characterized by high percentages of nonvolatile residues, which contain hydrocarbons, sterols, fatty acids, waxes, carotenoids, coumarins, psoralens, and flavonoids [8].

"Gold" Pressed Essential Oil: An Essay on the Volatile Fragment from Citrus Juice Industry By-Products Chemistry and Bioactivity

Psoralens must be used with caution because of their phototoxic properties; other known side effects of this class of drugs include nausea, pruritus and increased contrast between the lesion and normally pigmented skin.

Combination therapy of orally administered glycyrrhizin and UVB improved active-stage generalized vitiligo

(1,2) It is a nonimmune reaction caused by exposure to chemicals called furocoumarins and psoralens, found in a variety of plants and fruits such as lemons, limes, celery, parsnips, figs, carrots, dill, mustard, and rindweed.1,2

Phytophotodermatitis

The most frequently cited drugs that cause photo-onycholysis are tetracyclines, psoralens, and fluoroquinolones.