A range of novel PRTs for blood products that involve the combined use of ultraviolet light and reagents such as
psoralens or riboflavin are available (35,36).
Thereby,
psoralen makes the skin more sensitive to UV light where
psoralens intercalate within DNA.
Ondonsetron , Phenobarbitione, Rabies vaccine, Tetanus Immunoglobulin, Tramadol, Vancomycin, 5- methoxy
psoralens, Amlodepine , Atorvastatin, etc.
1,2) It is a nonimmune reaction caused by exposure to chemicals called furocoumarins and
psoralens, found in a variety of plants and fruits such as lemons, limes, celery, parsnips, figs, carrots, dill, mustard, and rindweed.
Psoralens are naturally occurring compounds that are activated to triplet states by UVA to produce therapeutic effects in various cutaneous disorders.
The most frequently cited drugs that cause photo-onycholysis are tetracyclines,
psoralens, and fluoroquinolones.
Other compounds that were reported to be photo-toxic are selected essential oils,
psoralens, sulfamides, coal tar derivatives and fluoroquinolones, as well as particular sunscreens such p-aminobenzoic acid, cinnamates and benzophenones.
3 Conservative therapies include photochemotherapy with
psoralens and ultraviolet A (PUVA), phototherapy alone with ultraviolet B (UVB) radiation (broadband UVB 290-320 nm, narrowband UVB (NBUVB) 311 nm), topical and systemic steroids and pseudocatalase.
European companies stopped using
psoralens as "tanning activators" in 1996, after studies reported that people who used
psoralen-containing sunscreens had a higher risk of melanoma.
Our findings are consistent with evidence from animal experiments, which revealed a potential synergistic effect between
psoralens and UV radiation, [but] further investigation is needed to confirm our findings and guide sun exposure behaviors among individuals with high citrus consumption.
Psoralens interact with ultraviolet light to stimulate the proliferation of melanoma cells.
Phototherapy combined with taking
psoralens is also effective.
