Chemical structures of compounds were envisioned consisting of three parts: pyridyl
moiety, a linker, and urea functional group as a pharmacophore (Scheme 1).
In our most recent work, we have commented on the possible use of the scaffold of sulfonated pyridyl
triazine complexes being utilized as serum albumin transporters .
(1979) Susceptibility of stored-product insects to pyridyl
ether analogues of juvenile hormone.
The compounds N-(ferrocenylmethyl)-N'-(2-methoxybenzyl) ethane-1,2-diamine dihydrochloride (4), N-(ferrocenyl-methyl)-N'-(pyridyl
)ethane-1,2-diamine trihydrochloride (7), and N-(7-chloroquinolin-4-yl)-N'-ferrocenylmethyl-1,2-diamine dihydrochloride (11) were synthesized as described elsewhere.
As ZnTPyP does not readily dissolve in water, its homogeneous stock solution (0.01 M) was prepared by dissolving an appropriate amount of ZnTPyP in HCl solution (0.2 M) to acidify its pyridyl
groups, forming soluble tetrapyridium cations.
Structures of Pyridyl
and Pyrimidyl analogues are shown in Figure 13.
A simple procedure for preparation of N-thiazol, thiadiazol, pyridyl
and sulfanylamidocantharidinimines analogues and evaluation of their cytotoxicities against human HL-60, MCF7, Neuro-2a and A549 carcinoma cells.
The working FRAP reagent was prepared by mixing 10 volumes of 300 mmol/L acetate buffer, pH 3.6, with 1 volume of 10 mmol/L TPTZ (2, 4, 6 Tris(pyridyl
)-s-triazine), (Sigma-Aldrich, St Louis, MO) in 40 mmol/L HCl and with 1 volume of 20 mmol/L FeCl3 prepared in deionized water.
Technetium-99m labeled pyridyl
benzofuran derivatives  was tested as potential probes for imaging [beta]-amyloid plaques in Alzheimer's brains using single photon emission computed tomography.
The GreenSep Pyridyl
Amide can separate compounds functionalized with both amine bases and acidic groups.
The synthesis of anilino (4a-h) and pyridyl
amino derivatives (7a-c) was carried out by refluxing (8-10 h) the reactant 1 and para substituted anilines (2, X = NH) or 2-amino pyridines (6) in the presence of ethanol as solvent.
where R is selected from [C.sub.1] to [C.sub.6] trial-kyl-silyl groups, [C.sub.1] to [C.sub.20] alkyl groups, [C.sub.4] to [C.sub.20] cycloalkyl groups, [C.sub.6] to [C.sub.20] aryl groups, thienyl, furyl, and pyridyl
groups; and R may optionally have attached thereto any of the following functional groups: [C.sub.1] to [C.sub.10] alkyl groups, [C.sub.6] to [C.sub.20] aryl groups, [C.sub.2] to [C.sub.10] alkenyl groups, [C.sub.3] to [C.sub.10] non-terminal alkynyl groups, ethers, tert-amines, oxazolines, thiazolines, phosphines, sulfides, silyls and mixtures thereof; where [R.sup.1] is selected from [C.sub.2] to [C.sub.80] alkylene groups, where X is NR, and where [pi] is a polymer chain.