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n.1.(Chem.) A hypothetical radical, C5H4N, regarded as the essential residue of pyridine, and analogous to phenyl.
Webster's Revised Unabridged Dictionary, published 1913 by G. & C. Merriam Co.
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Chemical structures of compounds were envisioned consisting of three parts: pyridyl moiety, a linker, and urea functional group as a pharmacophore (Scheme 1).
In our most recent work, we have commented on the possible use of the scaffold of sulfonated pyridyl triazine complexes being utilized as serum albumin transporters [39].
The compounds N-(ferrocenylmethyl)-N'-(2-methoxybenzyl) ethane-1,2-diamine dihydrochloride (4), N-(ferrocenyl-methyl)-N'-(pyridyl)ethane-1,2-diamine trihydrochloride (7), and N-(7-chloroquinolin-4-yl)-N'-ferrocenylmethyl-1,2-diamine dihydrochloride (11) were synthesized as described elsewhere.
As ZnTPyP does not readily dissolve in water, its homogeneous stock solution (0.01 M) was prepared by dissolving an appropriate amount of ZnTPyP in HCl solution (0.2 M) to acidify its pyridyl groups, forming soluble tetrapyridium cations.
A simple procedure for preparation of N-thiazol, thiadiazol, pyridyl and sulfanylamidocantharidinimines analogues and evaluation of their cytotoxicities against human HL-60, MCF7, Neuro-2a and A549 carcinoma cells.
The working FRAP reagent was prepared by mixing 10 volumes of 300 mmol/L acetate buffer, pH 3.6, with 1 volume of 10 mmol/L TPTZ (2, 4, 6 Tris(pyridyl)-s-triazine), (Sigma-Aldrich, St Louis, MO) in 40 mmol/L HCl and with 1 volume of 20 mmol/L FeCl3 prepared in deionized water.
Technetium-99m labeled pyridyl benzofuran derivatives [6] was tested as potential probes for imaging [beta]-amyloid plaques in Alzheimer's brains using single photon emission computed tomography.
The synthesis of anilino (4a-h) and pyridyl amino derivatives (7a-c) was carried out by refluxing (8-10 h) the reactant 1 and para substituted anilines (2, X = NH) or 2-amino pyridines (6) in the presence of ethanol as solvent.
where R is selected from [C.sub.1] to [C.sub.6] trial-kyl-silyl groups, [C.sub.1] to [C.sub.20] alkyl groups, [C.sub.4] to [C.sub.20] cycloalkyl groups, [C.sub.6] to [C.sub.20] aryl groups, thienyl, furyl, and pyridyl groups; and R may optionally have attached thereto any of the following functional groups: [C.sub.1] to [C.sub.10] alkyl groups, [C.sub.6] to [C.sub.20] aryl groups, [C.sub.2] to [C.sub.10] alkenyl groups, [C.sub.3] to [C.sub.10] non-terminal alkynyl groups, ethers, tert-amines, oxazolines, thiazolines, phosphines, sulfides, silyls and mixtures thereof; where [R.sup.1] is selected from [C.sub.2] to [C.sub.80] alkylene groups, where X is NR, and where [pi] is a polymer chain.