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A drug, C19H24N2O2, that kills trematodes and tapeworms parasitic to humans, used especially in the treatment of schistosomiasis.

[p(y)razi(ne), one of its constituents (from German Pyrazin, blend of Pyridin, pyridine Azin, azine) + qu(inoline) + ant(h)el(mintic).]


n praziquantel m, prazicuantel m (INN)
References in periodicals archive ?
Contract notice: Project management mission for the high voltage electrical safety of the lameynard site (pzq + mfme)
Two doses of oil was given (2.5 and 5 mL, two weeks, oral / kg) in a single dose or combination with Praziquantel (PZQ) which is preferred in the treatment of schistosomiasis.
Schistosomiasis control is heavily dependent on chemotherapy, using the only drug now available, praziquantel (PZQ) [4].
Lo anterior es importante puesto que se dispone de un numero limitado de medicamentos para el tratamiento de la esquistosomiasis, de los cuales el praziquantel (PZQ) es el menos costoso y hasta ahora el mas eficaz contra todas las especies de esquistosomas que infectan a los seres humanos (2, 3).
Background: Schistosomiasis is one of the world's major public health problems, and praziquantel (PZQ) is the only available drug to treat this neglected disease with an urgent demand for new drugs.
The existing gold standard' treatment for schistosomiasis is praziquantel (PZQ), which was developed by Merck KGaA, Darmstadt, Germany in the 1970s through a research collaboration.
In this study, we demonstrated the protective effect of berberine chloride (BER) in schistosomiasis-inducted oxidative stress on renal and testicular tissues of mice compared to praziquantel (PZQ).
The treatment of schistosomiasis is based on the control of adult worms in infected patients, with praziquantel (PZQ) being the most widely used drug.
Praziquantel (PZQ) is a pyrazinoisoquinoline drug used in both veterinary and human medicine as the drug of choice against many parasitic diseases caused by cestodes and trematodes.
A decrease occurred in titres of IgM and IgG antibodies against the total schizont antigen following praziquantel (PZQ) treatment (Figure 3(a)).
quantel (PZQ), which is used in the treatment of schistosomiasis (another illness primarily affecting people in the developing world).