Ollivier, "Antileishmanial activity of quinovic
acid glycosides and cadambine acid isolated from Nauclea diderrichii," Planta Medica, vol.
Besides the alkaloids, the triterpenic heterosides (derived from the quinovic acid) and polyphenols (especially tannin) are also highlighted (PAVEI et al., 2012; SHENG et al., 2005).
Triterpenes and quinovic acid glycosides from Uncaria tomentosa.
tomentosa s bark contains a series of secondary metabolites, such as oxindole alkaloids and polyphenols (flavonoids, proanthocyanidins, tannins) and small concentrations of other secondary metabolites, such as quinovic
acid glycosides, polyhydroxylated triterpenes and saponins (Laus, 2004; Aquino et al., 1990, Aquino et al., 1989).
Chemical studies have revealed the presence of alkaloids, quinovic
acid, glycosides, polyhydroxylated triterpenes, flavonoids and catechins in cat's claw, with some compounds showing a potentiation of phagocytosis by white blood cells.
1) include five known compounds; mono sodium salt of 3[beta],23-di-0-sulfonyl-23-hydroxyurs-20(21)-en-28-oic acid 28-0-[[beta]-D-glucopyranosyl] ester (Zygofaboside A; 1), (3[beta],4[alpha])-3,23,30-trihydroxyurs-20-en-28-al 3,23-di(sulfate) sodium salt (2), 3[beta]-0-[[beta]-D-2-0-sulfonylglucopyranosyl] quinovic
acid 28-0-[[beta]-D-glucopyranosyl]ester (Zygophyloside G; 3), 3-0-[2-0-sulfo-[beta]-D-quinovopyranoside] quinovic
acid 28-0-[[beta]-D-glucopyranosyl] ester (Zygophyloside E; 4), and 3[beta]-0-[[beta]-D-quinovopyranoside] quinovic
acid 28-0-[[beta]-D-glucopyranosyl] ester(5).
Uncaria tomentosa (Willd) DC., Rubiaceae, which is also known as cat's claw, contains more than 50 chemical constituents, including oxindole and indole alkaloids, polyphenols (flavonoids, proanthocyanidins, and tannins), glycosides, triterpenes derivatives quinovic
and quinic acid, and saponins .
Active components identified in these extracts include different oxindolic alkaloids, indole alkaloids, glycosides (pentacyclic triterpenes with a variety of derivatives such as ursolic acid, quinovic
acid glycosides, sterols and procianidins) and tannins the chemical composition of which can vary depending on their geographical origin and seasonal harvesting (Heitzman et al.
tomentosa revealed the presence of diverse compounds such as alkaloids, quinovic
acid glycosides, polyhydroxylated triterpenes, flavonoids, catechins and sterols (Aquino et al.
Cat's claw has been shown to contain many different chemical constituents, including quinovic
acid glycosides, sterols, tannins, procyanidins, flavonoids, polyhydroxylated triterpenes and at least 17 different alkaloids (Aquino et al., 1990; De Matta et al., 1976; Ganzera et al., 2001; Kitajima et al., 2002, 2003; Montoro et al., 2004; Muhammad et al., 2001a, b).
acid glycosides which have anti-viral activity (Cerri et al.
guianensis, and those which exist provide evidence only for its quinovic
acid glycoside and alkaloid content (Lee et al., 1999; Yepez et al., 1991).