(redirected from RET proto-oncogene)
Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.


v. ret·ted, ret·ting, rets
To moisten or soak (flax, for example) in order to soften and separate the fibers by partial rotting.
To become so moistened or soaked.

[Middle English reten, probably from Middle Dutch reeten.]


vb, rets, retting or retted
(Textiles) (tr) to moisten or soak (flax, hemp, jute, etc) to promote bacterial action in order to facilitate separation of the fibres from the woody tissue by beating
[C15: of Germanic origin; related to Middle Dutch reeten, Swedish röta, German rösten; see rot1]



v.t. ret•ted, ret•ting.
to soak, as flax, to facilitate the removal of the fiber from the woody tissue by rotting.
[1400–50; late Middle English ret(t)en]


1. retain.
2. retired.
3. return.
4. returned.


Past participle: retted
Gerund: retting

I ret
you ret
he/she/it rets
we ret
you ret
they ret
I retted
you retted
he/she/it retted
we retted
you retted
they retted
Present Continuous
I am retting
you are retting
he/she/it is retting
we are retting
you are retting
they are retting
Present Perfect
I have retted
you have retted
he/she/it has retted
we have retted
you have retted
they have retted
Past Continuous
I was retting
you were retting
he/she/it was retting
we were retting
you were retting
they were retting
Past Perfect
I had retted
you had retted
he/she/it had retted
we had retted
you had retted
they had retted
I will ret
you will ret
he/she/it will ret
we will ret
you will ret
they will ret
Future Perfect
I will have retted
you will have retted
he/she/it will have retted
we will have retted
you will have retted
they will have retted
Future Continuous
I will be retting
you will be retting
he/she/it will be retting
we will be retting
you will be retting
they will be retting
Present Perfect Continuous
I have been retting
you have been retting
he/she/it has been retting
we have been retting
you have been retting
they have been retting
Future Perfect Continuous
I will have been retting
you will have been retting
he/she/it will have been retting
we will have been retting
you will have been retting
they will have been retting
Past Perfect Continuous
I had been retting
you had been retting
he/she/it had been retting
we had been retting
you had been retting
they had been retting
I would ret
you would ret
he/she/it would ret
we would ret
you would ret
they would ret
Past Conditional
I would have retted
you would have retted
he/she/it would have retted
we would have retted
you would have retted
they would have retted
ThesaurusAntonymsRelated WordsSynonymsLegend:
Verb1.ret - place (flax, hemp, or jute) in liquid so as to promote loosening of the fibers from the woody tissue
souse, soak, sop, dowse, drench, douse - cover with liquid; pour liquid onto; "souse water on his hot face"


abbr of retireda. D.
References in periodicals archive ?
RET proto-oncogene has been identified in hereditary MEN2 syndrome, and is involved in sporadic medullary and papillary thyroid carcinoma (PTC) and Hirschsprung's disease (5).
(11-13) Further, reported molecular alterations involve the MET proto-oncogene (MET) and ret proto-oncogene (RET) genes.
Healey et al., "Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2 A," Nature, vol.
These 26 genes contained fibroblast growth factor receptor 1, G protein subunit alpha q, RB transcriptional corepressor 1, ABL proto-oncogene 1, B-Raf proto-oncogene, fibroblast growth factor receptor 3, guanine nucleotide-binding protein alpha stimulating ( GNAS ), HRas proto-oncogene ( HRAS ), fms-related tyrosine kinase 3, AKT serine/threonine kinase 1, ret proto-oncogene, cadherin 1 ( CDH1 ), cyclin-dependent kinase inhibitor 2A, HER2 , enhancer of zeste 2 polycomb repressive complex 2 subunit, isocitrate dehydrogenase 1, isocitrate dehydrogenase 2, MET proto-oncogene, mutL homolog 1 ( MLH1 ), neuroblastoma RAS viral oncogene homolog ( NRAS ), catenin beta 1, janus kinase 2, NOTCH1 , protein tyrosine phosphatase nonreceptor type 11, janus kinase 3, and MPL proto-oncogene.
Elisei, "A comprehensive overview of the role of the RET proto-oncogene in thyroid carcinoma," Nature Reviews.
The molecular alterations associated with PTC are BRAF mutations (50%), RET proto-oncogene rearrangements RET/PTC (10-30%), RAS mutations (15%).
Other multiplexed digital PCR designs have recently permitted researchers, for instance, to simultaneously target ALK (anaplastic lymphoma receptor tyrosine kinase), ROS1 (ROS proto-oncogene 1, receptor tyrosine kinase), and RET (ret proto-oncogene) fusions in lung cancer (24).
Hereditary syndromes of germline RET proto-oncogene mutations are the cause of MTC in the remaining 25-30% of patients.
Takahashi, "cDNA cloning of mouse ret proto-oncogene and its sequence similarity to the cadherin superfamily," Oncogene, vol.
In addition, future and ongoing clinical trials will not be limited to the targetable mutations described above and may involve mutations of other genes including ret proto-oncogene (RET) and HER2/neu.
Caption: THYROID CANCER RET proto-oncogene mutations increase risk.
Germline mutations in the RET proto-oncogene cause hereditary MTC [20-22], and approximately 50% of patients with sporadic MTC have somatic RET mutations [23, 24].