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Preventing tick bites is the most important step in preventing severe illness and death from RMSF.
24"W), Villeta town, an area of Cundinamarca, Colombia, to which RMSF is endemic.
RMSF is an acute disease, described as one of the most virulent human infections ever identified (Dumler & Walker 2005), and state health departments are required to report all cases to the Centers for Disease Control and Prevention (CDC).
Among 13 siblings of the cases, 2 had high titers of antibodies to Rickettsia rickettsii, the causative agent of RMSF.
A rash, the classic hallmark of RMSF, is present in 14% of patients on the first day of illness and in 49% during the first three days.
However, during 2008-2012, a total of 15 human RMSF cases (5-year average rate of 0.
Although RMSF is a noncontagious disease transmitted by tick bites, the physician did not warn the wife of the risk of exposure to RMSF.
Doctors often avoid prescribing doxycycline, the most effective RMSF treatment, for young children because the drug's warning label cautions that tooth staining may be a side effect in children younger than 8 years.
RMSF is referred to as Brazilian spotted fever in Brazil, where case-fatality rates are 20%-40% (1,2).
RMSF symptoms include arthritis-like stiffness and neurological problems.
In 2010, the Centers for Disease Control and Prevention and Council of State and Territorial Epidemiologists modified the RMSF case designation to spotted fever rickettsiosis, acknowledging the complex epidemiology of tick-borne rickettsioses (5).
By comparison, 6 of 10 persons with confirmed or probable RMSF in Jujuy during 1993-2004 died from this infection, and the surviving patients were hospitalized (21,22).