RNA interference


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Related to RNA interference: Sirna

RNA interference

n. Abbr. RNAi
A process in which double-stranded RNA inhibits the expression of genes by triggering degradation of messenger RNAs with complementary sequences.
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Researchers at the CSIRO lead a study that found genes can be switched off through RNA interference - which could mean that the sex of a chicken could be changed during development.
Summary: TEHRAN (FNA)- For the past decade, scientists have been pursuing cancer treatments based on RNA interference - a phenomenon that offers a way to shut off malfunctioning genes with short snippets of RNA.
They cover what RNA interference is; nucleic acids as regulatory molecules; using small-interference RNA (siRNA) oligonucleotides to study gene function; genome scanning by RNA interference; discovering new siRNA delivery agents; siRNA delivery vehicles; interferon, cytokine induction, and other potential in vivo toxicities; and applying RNA interference to viral disease.
of Western Ontario, Canada) and Ichim, an industry immunologist, compile 27 chapters describing current science and protocols in RNA interference (RNAi) for disciplines from detailed nucleic acid chemistry to pharmacology to manipulation of signal transduction pathways.
The researchers used structural biology to unravel how a small segment in the Argonaute proteins, the key molecules of RNA interference, can select the correct micro RNAs.
Nahum Sonenberg at McGill's new Life Sciences Complex, used structural biology to unravel how a small segment in the Argonaute proteins, the key molecules of RNA interference, can select the correct micro RNAs.
IS RNA INTERFERENCE INVOLVED IN PLANT-FUNGAL SYMBIOSIS?
SuperArray Bioscience Corporation (Frederick, MD) has entered into a RNA Interference (RNAi) license agreement with The Carnegie Institution.
The findings are part of efforts at Alnylam and other research groups to pit genetic technology called RNA interference, which won a 2006 Nobel Prize for two U.
Now, Rathore and his colleagues have used a technique called RNA interference (SN: 7/2/05, p.
RNA interference occurs in plants, animals, and humans.
The two partners will strive to confirm the efficacy of AIDS gene therapy using RNA interference enzymes.