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Related to RNase: RNase P, RNase H


 (är′ĕn-ās′, -āz′) also RNA·ase (är′ĕn-ā′ās′, -āz′)


(ˌraɪ boʊˈnu kliˌeɪs, -ˌeɪz, -ˈnyu-)

any of a class of enzymes that catalyze the hydrolysis of RNA. Also called RNase, RNAase.
ri`bo•nu•cle′ic, adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.RNase - a transferase that catalyzes the hydrolysis of ribonucleic acid
transferase - any of various enzymes that move a chemical group from one compound to another compound
References in periodicals archive ?
The method uses a thermophilic RNase H2 enzyme from Pyrococcus abyssi, which functions optimally in conditions compatible with thermophilic DNA polymerases, such as Taq polymerase.
In particular, a number of anthraquinone derivatives were reported to affect both HIV-1 RDDP and RNase H RT-associated functions in biochemical assays, but were not active on viral replication in cell-based assays (Tramontano et al.
The suppression of RNase L activity in cancer cell lines dramatically blocked cell death, according the researchers.
The OAS3 protein preferentially catalyzes the synthesis of dimeric 2'-5'-linked Oligoadenylate that binds to RNase L with lower affinity and induces less activation than the trimeric and longer oligomers synthesized by the OAS1 and OAS2 proteins.
Small amounts of RNase are sufficient to destroy RNA.
He said that now that they have the human RNase L structure, we can begin to understand the effects of carcinogenic mutations in the RNase L gene.
Normally, diethyl pyrocarbonate (DEPC) is added to the buffers and solutions required in order to inactivate RNases, which is tantamount to overkill, or excessive prevention of secondary contamination, such as that resulting from impure chemicals or materials.
Among these sequence studies, that of RNase A (124 residues) was most advanced and its amino acid sequence was determined in 1960 (13) with some revisions in 1962-1963.
The production medium (50-ml in a 250-ml Erlenmeyer flask) was inoculated with 5% of seed culture and flasks were placed on a rotary shaker at 180 rpm with 5 cm amplitude at 30[degrees]C for 120h to produce RNase.
RNase A 5mg/ml (500 [micro]l) is available from Carolina (211745).
Cloning, expression, and mapping of ribonucleases H of human and mouse related to bacterial RNase HI.