raltegravir


Also found in: Medical, Wikipedia.
Translations

raltegravir

n raltegravir m
References in periodicals archive ?
The authors note that raltegravir is usually taken twice a day, which may be more difficult for some patients.
With raltegravir having a twice-daily dosing schedule and elvitegravir being once daily, but with ritonavir boosting, it will be interesting to see what predicts greater usage.
s raltegravir, is an integrase inhibitor, which blocks viral genes from being incorporated into the host cell genome where they can be activated.
The NDA for elvitegravir is supported by 96-week data from a pivotal Phase 3 study (Study 145) in which elvitegravir (150 mg or 85 mg) dosed once daily was non-inferior to the integrase inhibitor raltegravir (400 mg) dosed twice daily, each administered with a background regimen that included a fully active ritonavir-boosted protease inhibitor and a second antiretroviral.
Raltegravir concentrations in CSF exceed the median inhibitory concentration.
Raltegravir plus atazanavir (with or without ritonavir)
The first drug to hit the market in this class is raltegravir (Isentress; Merck Sharp & Dohme (MSD)), which has generated the kind of excitement among treatment experts last seen with the onset of access to tenofovir or efavirenz.
The majority of viraemic patients with multi-drug-resistant HIV can now be suppressed when raltegravir is combined with other active agents.
The MAA for elvitegravir is supported by 96-week data from a pivotal Phase 3 study (Study 145) in which elvitegravir (150 mg or 85 mg) dosed once daily was non-inferior to the integrase inhibitor raltegravir (400 mg) dosed twice daily, each administered with a background regimen that included a ritonavir-boosted protease inhibitor and a second antiretroviral.
Tenders are invited for Conclusion of a non-exclusive rebate agreement pursuant to 130a (8) SGB V on the active substance Raltegravir, ATC code: J05AX08, for the period from 01.