immunoglobulin E(redirected from Reaginic antigen)
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Related to Reaginic antigen: reaginic antibody
n. Abbr. IgE
1. The class of antibodies that bind to mast cells and basophils and trigger them to release histamines and other substances that are responsible for allergic reactions. Immunoglobulin E antibodies are also thought to defend against parasitic worms.
2. An antibody of this class.
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|Noun||1.||immunoglobulin E - one of the five major classes of immunoglobulins; present primarily in the skin and mucous membranes|
Ig, immune gamma globulin, immune globulin, immune serum globulin, immunoglobulin - a class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response
reagin - an immunoglobulin E that is formed as an antibody against allergens (such as pollen); attaches to cell membranes causing the release of histamine and other substances responsible for the local inflammation characteristic of an allergy