Ombitasvir-paritaprevirritonavir plus dasabuvirvir* Viekira Pak XR Quetiapine-Seroquel Ribavirin * Rebetol
Sovaldi is usually given with ribavirin (Xolox, Copegus, Rebetol
, Ribasphere, Riba Tab) with or without peginter feronalfa (Pegasys, PegIntron).
Idenix currently has three hepatitis C drugs in clinical development, and Merck markets three hepatitis C medications: Victrelis, PegIntron and Rebetol
telaprevir (Incivek, Vertex Pharmaceuticals), an HCV genotype-1 protease inhibitor, combined with peginterferon alfa-2a (Pegasys, Genetech) plus ribavirin (Copegus, Genetech; Rebetol
, Merck; etc.
Boceprevir, in combination with PEGINTRON (peginterferon alfa-2b) and REBETOL
(ribavirin, USP) (Peg/riba), is being studied for the treatment of patients with HCV genotype 1 infection who were previously treated (treatment-failure; HCV RESPOND-2) and in patients who are new to treatment (treatment-naive; HCV SPRINT-2).
In both trials, patients also took two older drugs, Pegintron and Rebetol
, along with either the boceprevir or a placebo.
Table 2 Drugs for the Treatment of Chronic Hepatitis C Immunomodulators Interferon alfa-2a (Roferon[R], Roche Pharmaceuticals) interferon alfa-2b (Intron A[R], Schering Corporation) Interferon alfacon-1 (Infergen[R], Valeant Pharmaceuticals) Peginterferon alfa-2a (Pegasys[R], Roche Pharmaceuticals) Peginterferon alfa-2b (PegIntron[R], Schering Corporation) Antiviral Ribavirin (Copegus, Rebetol
, Ribasphere, and other manufacturers) Drugs Currently in Advanced Stages of Development * Albinterferon alfa-2b (Albuferon[R], Human Genome Sciences, Inc.
The company is a global leader in treatments for hepatitis C with its PEG-Intron, a onceweekly alpha interferon, combined with the Rebetol
That plant makes Zetia, for cholesterol control; Clarinex, an allergy medication; and Rebetol
, for hepatitis B.
2) With the approval of Peg-Intron and Rebetol
combination therapy in Japan in late 2004, sales of ribavirin increased from $18.
FDA approves Rebetol
(ribavarin) oral solution for treatment of children with chronic hepatitis C.
The first FDA-approved therapy for children with hepatitis C, Rebetol
Oral Solution (ribavirin), is now available.