Sevelamer (Renvela and Renagel
, Sanofi SA, Paris, France) is the newest member of the resin family.
Brand medications like Cipro HC, Lumigan, Sustiva, Renagel
, Welchol, Trevatan and Patanol have not reached the status of household recognized names.
The oral medicines used by dialysis patients include Amgen's Sensipar and two products from Genzyme, Renagel
and Renvela, which cut phosphate levels.
Alberta is the only province where Renagel
, an effect Albtive and safe therapy to control phosphorous levels in dialysis patients, is not publicly reimbursed, therefore limiting the specialists' access to it.
The company says in clinical study comparing Renvela to Renagel
both controlled serum phosphorus equally to within the recommended KDOQI range.
for allegedly infringing a patent used for its Renagel
Whitesides' innovation was Renagel
, a drug that binds the harmful phosphates eliminating the harmful metallic accumulation.
Renvela is being developed as a next generation phosphate binder to replace Renagel
(sevelamer hydrochloride), the most-prescribed phosphate binder in the United States.
Two polymer products have been brought to market, Renagel
(sevelamer hydrochloride), a calcium-free, metal-free phosphate binder for patients with end-stage renal disease, and WelChol (colesevelum hydrocholoride), a cholesterol-lowering agent.
Genzyme's new formulation of Renagel
, a dialysis drug, didn't generate the revenues that were expected.
There also was a 37% decrease in all-cause mortality in the RenaGel
group, but this trend did not achieve statistical significance, Dr.
To help prepare for a successful launch of the Neutrolin solution, which is planned initially in Germany, MKM hired as a national sales manager Joachim Petrak, who led the German and Central European launch of Renagel
(sevelamer), a phosphate binder used to control phosphorus levels in people with chronic kidney disease who are on dialysis.