renin

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re·nin

 (rē′nĭn, rĕn′ĭn)
n.
An enzyme released by the kidneys that cleaves a plasma protein to produce an inactive form of angiotensin which is then converted to an active form that raises blood pressure.

[Latin rēnēs, kidneys + -in.]

renin

(ˈriːnɪn)
n
(Biochemistry) a proteolytic enzyme secreted by the kidneys, which plays an important part in the maintenance of blood pressure
[C20: from reni- + -in]

re•nin

(ˈri nɪn)

n.
a proteolytic enzyme secreted by the kidneys that is involved in the release of angiotensin.
[< German Renin (1897) = Latin rēn(ēs) kidneys + German -in -in1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.renin - a proteolytic enzyme secreted by the kidneys; catalyzes the formation of angiotensin and thus affects blood pressure
peptidase, protease, proteinase, proteolytic enzyme - any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis
Translations

re·nin

[MIM*179820]
n. renina, enzima segregada por el riñón que interviene en la regulación de la presión arterial.
References in periodicals archive ?
Rarely, patients taking Tekturna developed an allergic reaction with swelling of the face, lips or tongue and difficulty breathing, as has been seen with other drugs for high blood pressure that act directly on the renin-angiotensin system.
We further have shown that the UP-induced pulmonary vasoconstriction could be inhibited by losartan, an A[T.sub.1]R antagonist, indicating that the renin-angiotensin system may play an important role.
Combined therapy with renin-angiotensin system and calcium channel blockers in type 2 diabetic hypertensive patients with proteinuria: effects on soluble TWEAK, PTX3, and flow-mediated dilation.
Dual blockade of the renin-angiotensin system versus maximal recommended dose of ACE inhibition in diabetic nephropathy.
Choi, "The renin-angiotensin system and aging in the kidney," Korean Journal of Internal Medicine, vol.
The renin-angiotensin system (RAS) is a peptidergic hormone system, which plays a central role in the pathophysiology of the eye.
Angiotensin II is the major bioactive component of the renin-angiotensin system and serves as one of the body's central regulators of blood pressure.
Activation of the renin-angiotensin system (RAS) is instrumental in regulating blood pressure and fluid balance.
All chapters have been revised and updated to include recent developments, such as the discovery of the major autoantigen in membranous nephropathy and the latest data on issues in therapeutics like blood pressure targets and the use of RAS (renin-angiotensin system) blockade.
1,25-Dihydroxyvitamin D3 is a negative endocrine regulator of the renin-angiotensin system. J Clin Invest 2002;110:229-38.
In another report, renin-angiotensin system antagonists did reduce mortality in patients who had HF with preserved ejection fraction, after clinical trials had indicated the drugs would not do so.
Two trials of aliskiren in combination with another renin-angiotensin system blocker in heart failure patients are ongoing, the researchers said.